TETANUS TOXIN C FRAGMENT
TETANUS TOXIN C FRAGMENT 物理性質
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H311 |
皮膚に接触すると有毒 |
急性毒性、経皮 |
3 |
危険 |
|
P280, P302+P352, P312, P322, P361,P363, P405, P501 |
|
| 注意書き |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
|
TETANUS TOXIN C FRAGMENT 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
TETANUS TOXIN C FRAGMENT 化学特性,用途語,生産方法
使用
The C terminal binding portion of tetanus toxin is not toxic but is taken up by pre-synaptic nerve terminals and exhibits trans-synaptic retrograde transport in central neurons similar to that of tetanus toxin. It is used to map neuronal connections and to target proteins to neurons.
一般的な説明
Tetanus toxin C fragment (TTC) is a non-toxic peptide, which is transported from peripheral axons into spinal motoneurons. It provides protection for motoneurons (MN) in the spinal cord
in vivo. TTC regulates membrane binding, internalization and retrograde transport within MN. It initiates neurotrophin-regulated signaling pathways in a Trk receptor-dependent manner. TTC has neuroprotective property in primary cerebellar granule cell culture.
Biochem/physiol Actions
Tetanus toxin is a neurotoxin that comprises of a heavy and a light chain linked by disulfide bridges. This neurotoxin enters the cytoplasm and releases the light chain component that subsequently inhibits the release of neurotransmitters2. Studies have reported that the fragment C of tetanus toxin retains most of the determinants that interact with thyroid membranes, gangliosides and neural membranes3.
TETANUS TOXIN C FRAGMENT 上流と下流の製品情報
原材料
準備製品
TETANUS TOXIN C FRAGMENT 生産企業
Global( 15)Suppliers
- TSTX-K-ALPHA-TTC
- TETANUS TOXIN C FRAGMENT
- TETANUS TOXIN, C-FRAGMENT, CLOSTRIDIUM TETANI
- TETANUS TOXIN C-FRAGMENT RECOMBINANT
- RTTC
- Tetanus toxin C fragment from Clostridium tetani
- TTC