ALA-TYR-PRO-GLY-LYS-PHE-NH2 トリフルオロアセタート塩

ALA-TYR-PRO-GLY-LYS-PHE-NH2 トリフルオロアセタート塩 価格 もっと(1)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	A3227	Ala-Tyr-Pro-Gly-Lys-Phe-NH2 トリフルオロアセタート塩 ≥98% (HPLC), solid Ala-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt ≥98% (HPLC), solid		1mg	￥49800	2024-03-01	購入

ALA-TYR-PRO-GLY-LYS-PHE-NH2 トリフルオロアセタート塩 化学特性,用途語,生産方法

使用

4-Androsten-11β-ol-3,17-dione has been used in platelet aggregation.

一般的な説明

Ala-Tyr-Pro-Gly-Lys-Phe-NH₂ (AYPGKF- NH₂) is a selective, specific proteinase-activated receptor 4 (PAR4) agonist peptide. PAR4 is a G-protein-coupled receptor that is expressed on the surface of human platelets and is involved in the thrombin signaling pathway. Cleavage of PAR4 by the protease thrombin stimulates the receptor and results in signaling of platelet aggregation.

Biochem/physiol Actions

AYPGK is a ligand for the PAR4 receptor; binding results in activation of PAR4. AYPGK stimulates platelet aggregation in vitro (EC50 =15 μM) via PAR4. In human platelets treated with the PAR4 agonist, AYPGKF stimulates the production of thromboxane, a potent agent for platelet-aggregation. Additionally, AYPGKF mediates the thrombin-induced release of endostatin from rat platelets.

ALA-TYR-PRO-GLY-LYS-PHE-NH2 トリフルオロアセタート塩 上流と下流の製品情報

原材料

準備製品

ALA-TYR-PRO-GLY-LYS-PHE-NH2 トリフルオロアセタート塩 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Riedel-de Haen AG	--		United States	6773	87
SIGMA-RBI	--		Switzerland	6896	91

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• AYPGKF-NH2, PAR4-AP
• ALA-TYR-PRO-GLY-LYS-PHE-NH2 TRIFLUOROACETATE SALT
• AYPGKF-NH2 TFA SALT
• PAR4-AP TFA SALT
• ALA-TYR-PRO-GLY-LYS-PHE-NH2 トリフルオロアセタート塩