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ミロガバリンベシル酸塩

ミロガバリンベシル酸塩 化学構造式
1138245-21-2
CAS番号.
1138245-21-2
化学名:
ミロガバリンベシル酸塩
别名:
ミロガバリンベシル酸塩;ミロガバリンベシル酸塩 (JAN)
英語名:
Mirogabalin besylate
英語别名:
Mirogabalin Besilate;Mirogabalin besylat;Mirogabalin besylate;Mirogabalin Besylate 10928;MIROGABALIN BENZENESULFONIC ACID;Mirogabalin besylate (DS 5565 besylate);2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid besylate;[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0] hept-3-en-6-yl]acetic acid benzenesulfonate;((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate;2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid compound with benzenesulfonic acid (1:1)
CBNumber:
CB73175483
化学式:
C18H25NO5S
分子量:
367.46
MOL File:
1138245-21-2.mol

ミロガバリンベシル酸塩 物理性質

貯蔵温度 :
Store at -20°C
溶解性:
DMSO : 125 mg/mL (340.17 mM)
外見 :
Solid
色:
White to off-white
InChI:
InChI=1/C12H19NO2.C6H6O3S/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8;7-10(8,9)6-4-2-1-3-5-6/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15);1-5H,(H,7,8,9)/t9-,10-,12-;/s3
InChIKey:
OKJXJRVWXYRSAN-QWGAVYBYNA-N
SMILES:
S(C1C=CC=CC=1)(O)(=O)=O.C([C@]1(C[C@@]2([H])CC(CC)=C[C@@]12[H])CN)C(=O)O |&1:11,13,20,r|

安全性情報

ミロガバリンベシル酸塩 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

ミロガバリンベシル酸塩 化学特性,用途語,生産方法

効能

疼痛治療

商品名

タリージェ (第一三共)

説明

Mirogabalin besylate (mirogabalin, Tarlige) is a gabapentinoid therapy developed by Daiichi Sankyo, which is approved in Japan for the treatment of postherpetic neuralgia and painful diabetic peripheral neuropathy. Mirogabalin has a potent pain-modulating effect with a unique high affinity and prolonged dissociation rate for the a2delta-1 subunit of voltage-gated calcium (Ca2+) channels (VGCCs) on the dorsal root ganglion resulting in more sustained analgesia compared with traditional gabapentinoids[1].

使用

Mirogabalin besylate is an oral gabapentin analogue for the treatment of peripheral neuralgia (PNP), including diabetic PNP and postherpetic neuralgia. The drug has been approved in Japan for the treatment of PNP and has not yet received FDA approval.

ミロガバリンベシル酸塩 上流と下流の製品情報

原材料

準備製品

ミロガバリンベシル酸塩 生産企業

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  • 1138245-21-2
  • Mirogabalin besylate
  • Mirogabalin besylat
  • MIROGABALIN BENZENESULFONIC ACID
  • ((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate
  • [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0] hept-3-en-6-yl]acetic acid benzenesulfonate
  • 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid compound with benzenesulfonic acid (1:1)
  • Mirogabalin Besylate 10928
  • Mirogabalin besylate (DS 5565 besylate)
  • Mirogabalin Besilate
  • 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid besylate
  • ミロガバリンベシル酸塩
  • ミロガバリンベシル酸塩 (JAN)
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