3,4-ジメチル-3H-イミダゾ[4,5-f]キノリン-2-アミン 化学特性,用途語,生産方法
外観
白色～褐色, 結晶性粉末～粉末
溶解性
エタノール及びアセトンに溶け、水にほとんど溶けない。
用途
変異原性・がん原性物質試験研究用。
化学的特性
Yellow Crystalline Solid
使用
Mutagenic heterocyclic amines in cooked food
調製方法
Heterocyclic amines are formed by condensation of creatinine
with amino acids during heating or cooking of meat
(beef, pork, chicken, and fish). They have also been detected
in processed food flavorings, beer, wine, and cigarette smoke.
2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) and
related heterocyclic amines are produced in small quantities
for research purposes. Exposure to MeIQ and related
heterocyclic amines occurs primarily through the consumption
of cooked meats.Concentrations of heterocyclic
amines in meats varied under different cooking conditions
(375). The highest concentrations of MeIQ were
detected in grilled fish, which appear to be the major dietary
source of heterocyclic amines in Japanese. U.S. surveys
of dietary intakes of heterocyclic amines in cooked
foods have also been reported. Occupational exposure
to heterocyclic amines may occur by inhalation of aerosolized
particles formed during the cooking process.
一般的な説明
Pale orange crystalline solid or light yellow powder.
空気と水の反応
2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is sensitive to light and air. Slightly water soluble .
反応プロフィール
2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is rapidly degraded by dilute hypochlorite.
健康ハザード
ACUTE/CHRONIC HAZARDS: 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE may emit potentially toxic fumes when involved in a fire.
火災危険
Flash point data for 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE are not available; however, 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is probably combustible.
安全性プロファイル
Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
発がん性
MeIQ is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.
3,4-ジメチル-3H-イミダゾ[4,5-f]キノリン-2-アミン 上流と下流の製品情報
原材料
準備製品