シブトラミン塩酸塩一水和物
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- CAS番号.
- 125494-59-9
- 化学名:
- シブトラミン塩酸塩一水和物
- 别名:
- シブトラミン塩酸塩一水和物;シブトラミン塩酸塩一水和物標準品;シブトラミン塩酸塩水和物;シブトラミン塩酸塩水和物 (JAN)
- 英語名:
- SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
- 英語别名:
- SIBUTRAMINE HCL MONOHYDRATE;Sibutramine sib;SibutramineHClH2O;SIBUTRAMINE HCL HYDRATE;)-SibutraMine-d6 HCl H2O;BTS-54524, Reductil, Meridia;SIBUTRAMINE HYDROCHLORIDE HYDRATE;Sibutramine hydrochloride solution;Sibutramine Hydrochloride Monohydra;SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
- CBNumber:
- CB8708494
- 化学式:
- C17H29Cl2NO
- 分子量:
- 334.32
- MOL File:
- 125494-59-9.mol
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シブトラミン塩酸塩一水和物 物理性質
- 融点 :
- 193-195.5°C
- 闪点 :
- 9℃
- 貯蔵温度 :
- Room temp
- 溶解性:
- DMSO：>30mg/mL
- 外見 :
- 個体
- 色:
- 白い
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
  
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| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H225 |
引火性の高い液体および蒸気 |
引火性液体 |
2 |
危険 |
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P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H370 |
臓器の障害 |
特定標的臓器有害性、単回暴露 |
1 |
危険 |
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P260, P264, P270, P307+P311, P321,P405, P501 |
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| 注意書き |
| P210 |
熱/火花/裸火/高温のもののような着火源から遠ざ けること。－禁煙。 |
| P260 |
粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P301+P310 |
飲み込んだ場合：直ちに医師に連絡すること。 |
| P311 |
医師に連絡すること。 |
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シブトラミン塩酸塩一水和物 化学特性,用途語,生産方法
効能
食欲抑制薬, 抗うつ薬, セロトニン・ノルアドレナリン再取り込み阻害薬
説明
Sibutramine was introduced as Meridia in the US for the control of
obesity, in conjunction with a reduced-calorie diet. Sibutramine can be prepared
in four steps from 4-chlorobenzyl cyanide. Sibutramine acts as a serotonin and
noradrenaline reuptake inhibitor ; in animal studies, it reduces energy intake by
creating a satieted feeling and increases energy expenditure by enhancing
thermogenesis. In a clinical study in obese patients treated with 10 or 15 mg of
Sibutramine once-daily, meaningful weight loss was sustained for 12 months ;
an additional study demonstrated a lack of abuse potential. An appreciable part
of Sibutramine's effect would also be due to its 2N-mono and didesmethylmetabolites,
which are very potent monoamine reuptake inhibitors
themselves.
化学的特性
White Solid
使用
A serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure
シブトラミン塩酸塩一水和物 上流と下流の製品情報
原材料
準備製品
125494-59-9(シブトラミン塩酸塩一水和物)キーワード:
- 125494-59-9
- [1-[1-(4-chlorophenyl)cyclobutyl]-3-methyl-butyl]-dimethyl-amine hydrate hydrochloride
- 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine hydrate hydrochloride
- 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrate hydrochloride
- 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
- Sibutramine Hydrochloride CIV (125 mg)
- )-SibutraMine-d6 HCl H2O
- 1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride
- CyclobutaneMethanaMine,1-(4-chlorophenyl)-N,N-diMethyl-a-(2-Methylpropyl)-, hydrochloride, hydrate (1:1:1)
- Sibutramine hydrochloride solution
- SibutramineHClH2O
- BTS-54524, Reductil, Meridia
- Meridia, Reductil, 1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine monohydrate hydrochloride
- Sibutramine monohydrate hydrochloride
- SIBUTRAMINE HCL HYDRATE
- SIBUTRAMINE HYDROCHLORIDE HYDRATE
- SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE
- 1-(1-(4-chlorophenyl)cyclobutyl)-N,N,3-trimethylbutan-1-amine hydrochloride hydrate
- Sibutramine sib
- Sibutramine Hydrochloride Monohydrate Standard
- Sibutramine Hydrochloride Monohydra
- Sibutramine hydrochloride solution in Methanol，1000ug/ml
- Sibutramine Hydrochloride MonohydrateQ: What is
Sibutramine Hydrochloride Monohydrate Q: What is the CAS Number of
Sibutramine Hydrochloride Monohydrate Q: What is the storage condition of
Sibutramine Hydrochloride Monohydrate Q: What are the applications of
Sibutramine Hydrochloride Monohydrate
- Sibutramine Hydrochloride CIV (1612845)
- SIBUTRAMINE HCL MONOHYDRATE
- シブトラミン塩酸塩一水和物
- シブトラミン塩酸塩一水和物標準品
- シブトラミン塩酸塩水和物
- シブトラミン塩酸塩水和物 (JAN)
- 生活関係標準物質
- 食料品