セベラマー 化学特性,用途語,生産方法
効能
高リン血症治療薬
使用
Antihyper-phosphatemic.
brand name
Renagel (Genzyme).
応用例(製薬)
In patients on dialysis, Sevelamer or lanthanum salts can be used to maintain normal phosphate blood levels. Sevelamer is a polymer containing amine
groups. These protonated amine groups can react with the negatively charged phosphate groups via ionic binding
and prevent absorption of phosphate from the gut. Sevelamer is a hydrogel containing cross-linked polyallylamine chains. The negatively charged phosphate can be bound to the positively charged amine groups of the hydrogel in the intestines and removed via the faeces.
セベラマー 上流と下流の製品情報
原材料
準備製品