[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド
[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド 物理性質
- 貯蔵温度 :
- −20°C
- 溶解性:
- ≥128.7 mg/mL in DMSO; ≥128.6 mg/mL in EtOH; ≥128.8 mg/mL in H2O
- 外見 :
- 粉
- 色:
- White to off-white
- シーケンス:
- Glu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
- InChIKey:
- IMRONVSKLHSCMF-VWCBMNBRNA-N
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 主な危険性 |
T |
|
|
| Rフレーズ |
60 |
|
|
| Sフレーズ |
53-45 |
|
|
| WGK Germany |
3 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
|
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H360 |
生殖能または胎児への悪影響のおそれ |
生殖毒性 |
1A, 1B |
危険 |
|
|
|
| 注意書き |
|
[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド 価格
もっと(3)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MPB02152917 |
[D-Ala6,Des-Gly10]-性腺刺激ホルモン放出ホルモンエチルアミド
[D-Ala6, Des-Gly10]-Luteinizing Hormone-Releasing Hormone Ethylamide TFA SALT |
79561-22-1 |
1mg |
￥32000 |
2018-12-26 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MPB02152917 |
[D-Ala6,Des-Gly10]-性腺刺激ホルモン放出ホルモンエチルアミド
[D-Ala6, Des-Gly10]-Luteinizing Hormone-Releasing Hormone Ethylamide TFA SALT |
79561-22-1 |
5mg |
￥111000 |
2018-12-26 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MPB02152917 |
[D-Ala6,Des-Gly10]-性腺刺激ホルモン放出ホルモンエチルアミド
[D-Ala6, Des-Gly10]-Luteinizing Hormone-Releasing Hormone Ethylamide TFA SALT |
79561-22-1 |
25mg |
￥427000 |
2018-12-26 |
購入 |
[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド 化学特性,用途語,生産方法
細胞毒性(Cytotoxicity)
Cell Assay
The cells are trypsinized in a solution of 2.5 g/L trypsin and seeded in a 96-well plate. After the cells are grown for 24 h to approximately 800 g/L subconfluent state, 0.1 mL medium containing 2.5% calf serum and various concentrations (0.001, 0.1, 10 μM) of alarelin is added to each well, respectively, and incubated for 24 h in a CO2 incubator. Each concentration is tested in at least 12 wells. Briefly, 15 μL of MTT solution is added to each well and incubated for 4 h. Then, the medium and MTT are removed and 150 μL of DMSO is added to each well and shaken for 10 min to dissolve the crystal. The OD is determined at 490 nm using an ELISA reader.
Animal Administration
Rats: Male Sprague-Dawley rats are divided into two groups. In Group I: Gastric acid secretion is measured in a chambered stomach. Briefly, the abdomen is incised, and both the stomach and duodemun are exposed and tied respectively; then 1.5 mL 0.9% sodium chloride (containing Alarelin, 2 μg/kg) is infused into the each chambered stomach. After 15, 30, 45, 60 min, the gastric juice is drew out of the chambered stomach and the pH is measured in the ABL-500 respectively. The control is infused saline instead of Alarelin. In Group II: After anaesthetized, 2 mL Alarelin (2 μg/kg) is administered into the tail vein. The control is injected the saline instead of Alarelin. Then, the stomach and duodenum are tied and infused 1.5 mL saline immediately. After 15, 30, 45, 60 min, the gastric juice is also drew out of the chambered stomach and the pH is measured in the ABL-500 respectively.
[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド 上流と下流の製品情報
原材料
準備製品
[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド 生産企業
Global( 331)Suppliers
[D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド スペクトルデータ(MS)
79561-22-1([D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド)キーワード:
- 79561-22-1
- [des-Gly10, D-Ala6]-LH-RH ethylamide hydrate acetate salt
- Amp:Adenosine-5-MonophosphateFreeAcid
- HO-Glp-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHCH2CH3
- Alareline Acetate
- 6-D-Ala-10-D-gly-LHRH-ethylaMide
- DES-GLY10,[D-ALA6]-LH-RH ETHYLAMIDE ACETATE SALT
- (DES-GLY10,D-ALA6,PRO-NHET9)-LHRH
- ALARELIN
- PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET
- (DES-GLY10,D-ALA6,PRO-NHET9)-GONADOTROPIN-RELEASING HORMONE (SEA BREAM)
- (DES-GLY10,D-ALA6,PRO-NHET9)-GONADOTROPIN-RELEASING HORMONE
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR
- (DES-GLY10,D-ALA6,PRO-NHET9)-LHRH (SEA BREAM)
- [DES-GLY10, D-ALA6, PRO-NHET9]-LH-RH (HUMAN)
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING HORMONE
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING HORMONE (SEA BREAM)
- [DES-GLY10, D-ALA6, PRO-NHET9]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN)
- [DALA6,DES-GLY10] LUTEINIZING HORMONE-RELEASING HORMONE, ETHYL AMIDE
- [D-ALA6,DES-GLY10]-LH-RH ETHYLAMIDE
- GLP-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET
- SURFAGON
- PGLU-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET ACETATE SALT
- N-[1-[[1-[[1-[[1-[1-[[1-[[1-[2-(ETHYLCARBAMOYL)PYRROLIDIN-1-YL]CARBONYL-4-GUANIDINO-BUTYL]CARBAMOYL]-3-METHYL-BUTYL]CARBAMOYL]ETHYLCARBAMOYL]-2-(4-HYDROXYPHENYL)-ETHYL]CARBAMOYL]-2-HYDROXY-ETHYL]CARBAMOYL]-2-(1H-INDOL-3-YL)ETHYL]CARBAMOYL]-2-(3H-IMIDAZOL-4-YL)ETHYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE
- des-gly10(D-ala6) luteinizing hormone*releasing H
- (DES-GLY10 D-ALA6)-LH-RH ETHYLAMIDE ACE
- LHRH, Ala(6)-Gly(10)-ethylamide-
- pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
- Alarelin impurity
- Allah Lin
- Alarelin USP/EP/BP
- [D-ALA6,DES-GLY10]-性腺刺激ホルモン放出ホルモンエチルアミド
- 5-オキソ-Pro-HIs-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt
- (2S)-1-[(2S)-5-カルバムイミドアミド-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-3-ヒドロキシ-2-[(2S)-3-(1H-インドール-3-イル)-2-{[(2S)-5-オキソピロリジン-2-イル]ホルムアミド}プロパンアミド]プロパンアミド]-3-(4-ヒドロキシフェニル)プロパンアミド]プロパンアミド]-4-メチルペンタンアミド]ペンタノイル]-N-エチルピロリジン-2-カルボキサミド
- アラレリン