2-シアノフェノール
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
 
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
| H317 |
アレルギー性皮膚反応を起こすおそれ |
感作性、皮膚 |
1 |
警告 |
|
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H318 |
重篤な眼の損傷 |
眼に対する重篤な損傷性/眼刺激 性 |
1 |
危険 |
|
P280, P305+P351+P338, P310 |
|
| 注意書き |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
|
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01AFAA13606 |
2-ヒドロキシベンゾニトリル, 98%
2-Hydroxybenzonitrile, 98% |
611-20-1 |
5g |
￥9170 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01AFAA13606 |
2-ヒドロキシベンゾニトリル, 98%
2-Hydroxybenzonitrile, 98% |
611-20-1 |
25g |
￥29100 |
2024-03-01 |
購入 |
|
東京化成工業
|
C1045 |
2-シアノフェノール >98.0%(GC)(T)
2-Cyanophenol
>98.0%(GC)(T) |
611-20-1 |
5g |
￥4700 |
2024-03-01 |
購入 |
|
東京化成工業
|
C1045 |
2-シアノフェノール >98.0%(GC)(T)
2-Cyanophenol
>98.0%(GC)(T) |
611-20-1 |
25g |
￥13300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
18434-52 |
2-Hydroxybenzonitrile |
611-20-1 |
5g |
￥5500 |
2024-07-01 |
購入 |
2-シアノフェノール 化学特性,用途語,生産方法
外観
淡黄色～褐色、結晶～結晶性粉末
用途
有機合成原料。
説明
Cyanophenol is a vital molecule widely used to synthesize liquid crystal materials, medicines, spices, pesticides, corrosion inhibitors, etc. Cyanophenol is formed by substituting two hydrogen atoms of benzene molecules with hydroxyl and cyano groups, respectively. The cyano and hydroxyl groups are in the ring plane in the stable molecular structure. The hydroxyl group can have two different orientations relative to the cyano group. 2-cyanophenol, one of the Cyanophenol, is an essential ingredient in pesticides, spices, liquid crystal materials, etc. It is an especially critical intermediate for synthesizing methoxyacrylate fungicide mystrostrobin, widely used in agrochemicals, pharmaceutical chemicals, and other industries. The cyano group can strongly attract electrons. Replacing a hydrogen atom of the benzene ring by the cyano group usually increases the ionization energy (IE)[1].
化学的特性
2-Cyanophenol is a white to light yellow crystal powder with a pungent and bitter odor. It is partially soluble in water with a Pka value of 7.17. However, it is unstable when exposed to strong alkalis and oxidants. It is an important intermediate for the synthesis of the fungicide azoxystrobin and the antihypertensive drug Bunirolol.
使用
2-Hydroxybenzonitrile is used as starting reagent during the synthesis of mono-alkoxyphenyloxazoline, furanoside.
主な応用
2-Cyanophenol is used in the synthesis of CDK/GSK-3 inhibitors, for usage as therapeutics in Alzheimer's disease (AD).
合成
2-Hydroxybenzonitrile can be synthesized by condensing salicylaldehyde with hydroxylamine hydrochloride to produce salicylaldoxime. Then, the salicylaldoxime is reacted with acetic anhydride followed by hydrolysis to yield 2-Hydroxybenzonitrile.
Process for the preparation of 2-hydroxybenzonitrile
貯蔵
Store at 2°C - 8°C, close container well, protect from light.
2-シアノフェノール 上流と下流の製品情報
原材料
準備製品
2-シアノフェノール 生産企業
Global( 639)Suppliers
2-シアノフェノール スペクトルデータ(1HNMR、13CNMR、IR1、IR2、MS、Raman)
611-20-1(2-シアノフェノール)キーワード:
- 611-20-1
- 2-Hydroxybenzonitrile, 97+%
- 2-Cyanophenol SynonyMs: 2-Hydroxybenzonitrile
- O-hydroxybanzo nitrile
- O-HYDROXYBENZONITRILE
- SALICYLIC ACID NITRILE
- SALICYLONITRILE
- 2-CYANOPHENOL (2-HYDROXYBENZONITRILE)
- O-HYDROXYBENZONITRIL
- 2-Cyanophenol, Salicylonitrile
- 2-Cyanophenol,99%
- Benzene, 1-chloro-3-fluoro-2-(trichloromethyl)-
- 2-Hydroxybenzonitrile ,99%
- 2-Cyanophenol, 99% 25GR
- 2-Cyanophenol, 99% 5GR
- 2-hydroxy-benzonitril
- Benzonitrile, o-hydroxy-
- o-Hydoxybenzonitrile
- 2-CYANOPHENOL
- 2-Hydroxybenzonitrile,98%
- Benzonitrile, 2-hydroxy-
- 2-Hydroxybenzonitrile (o-Hydroxybenzonitrile
- Febuxostat Impurity 107
- 2-Cyanophenol >
- 2-Cyanopheno
- O-CYANOPHENOL
- Salicylnitrile
- 2-HYDROXYBENZONITRILE
- CYANOPHENOL
- TIMTEC-BB SBB007959
- Ortho hydroxybenzonitrile
- 2-シアノフェノール
- 2-ヒドロキシベンゾニトリル
- o-ヒドロキシベンゾニトリル
- o-シアノフェノール
- サリチロニトリル
- ２シアノフエノル
- 2‐シアノフェノール
- 2-ヒドロキシベンゾニトリル, 98%