セフピミゾール

セフピミゾール 化学構造式
84880-03-5
CAS番号.
84880-03-5
化学名:
セフピミゾール
别名:
セフピミゾール;1-[[(6R)-2-カルボキシラト-7α-[[(R)-[[(5-カルボキシ-1H-イミダゾール-4-イル)カルボニル]アミノ]フェニルアセチル]アミノ]-8-オキソ-5-チア-1-アザビシクロ[4.2.0]オクタ-2-エン-3-イル]メチル]-4-(2-スルホエチル)ピリジニウム;1-{[(6R,7R)-7-[(2R)-2-[(5-カルボキシ-1H-イミダゾール-4-イル)ホルムアミド]-2-フェニルアセトアミド]-2-カルボキシラト-8-オキソ-5-チア-1-アザビシクロ[4.2.0]オクタ-2-エン-3-イル]メチル}-4-(2-スルホエチル)ピリジン-1-イウム
英語名:
Cefpimizole
英語别名:
A-1370;U 63196;Cefpimizol;CEFPIMIZOLE;Cefpimizole USP/EP/BP;1-[[(6R)-2-Carboxylato-7α-[[(R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)pyridinium;Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt;Pyridinium,1-[[(6R,7R)-2-carboxy-7-[[(2R)-2-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-,inner salt;(6R,7R)-7-[[(2R)-2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenylacetyl]amino]-8-oxo-3-[[4-(2-sulfonatoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, [6R-[6α,7β(R*)]]-
CBNumber:
CB9314975
化学式:
C28H26N6O10S2
分子量:
670.67
MOL File:
84880-03-5.mol

セフピミゾール 物理性質

安全性情報

セフピミゾール 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

セフピミゾール 化学特性,用途語,生産方法

効能

抗生物質

説明

Cefpimizole sodium is a third-generation cephalosporin with a spectrum of activity somewhat narrower than cefotaxime and cefoperazone.

使用

Antibacterial.

抗菌性

A semisynthetic parenteral cephalosporin. It exhibits modest activity compared to other antipseudomonal cephalosporins. Like cefoperazone, it is susceptible to many enterobacterial β-lactamases. In volunteers receiving 0.1–1 g intramuscularly, mean peak plasma concentrations reached 15–20 and 35–40 mg/L, respectively. There was no accumulation when the dose was repeated every 8 h for 7 days. No metabolites have been detected. The plasma elimination half-life is 1.8– 2.1 h. The principal route of elimination is renal, 70–80% being recovered unchanged in the urine.
Significant pain at the site of infection has been a prominent adverse event. It is no longer widely available.

セフピミゾール 上流と下流の製品情報

原材料

準備製品


セフピミゾール 生産企業

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84880-03-5(セフピミゾール)キーワード:


  • 84880-03-5
  • Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt
  • Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, [6R-[6α,7β(R*)]]-
  • U 63196
  • (6R,7R)-7-[[(2R)-2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenylacetyl]amino]-8-oxo-3-[[4-(2-sulfonatoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • CEFPIMIZOLE
  • 1-[[(6R)-2-Carboxylato-7α-[[(R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)pyridinium
  • Cefpimizol
  • cefpimizole:(6r,7r)-7-(((2r)-2-((5-carboxy-1h-IMIDAZOLE-4-carbonyl)amino)-2-phenylacetyl)amino)-8-oxo-3-((4-(2-sulfonatoethyl)pyridin-1-ium-1-yl)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxyli
  • Cefpimizole USP/EP/BP
  • A-1370
  • Pyridinium,1-[[(6R,7R)-2-carboxy-7-[[(2R)-2-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-,inner salt
  • セフピミゾール
  • 1-[[(6R)-2-カルボキシラト-7α-[[(R)-[[(5-カルボキシ-1H-イミダゾール-4-イル)カルボニル]アミノ]フェニルアセチル]アミノ]-8-オキソ-5-チア-1-アザビシクロ[4.2.0]オクタ-2-エン-3-イル]メチル]-4-(2-スルホエチル)ピリジニウム
  • 1-{[(6R,7R)-7-[(2R)-2-[(5-カルボキシ-1H-イミダゾール-4-イル)ホルムアミド]-2-フェニルアセトアミド]-2-カルボキシラト-8-オキソ-5-チア-1-アザビシクロ[4.2.0]オクタ-2-エン-3-イル]メチル}-4-(2-スルホエチル)ピリジン-1-イウム
  • セファロスポリン類
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