6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 化学構造式
36067-72-8
CAS番号.
36067-72-8
化学名:
6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩
别名:
6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩;B-HT-933;6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン・2塩酸塩
英語名:
B-HT 933 DIHYDROCHLORIDE
英語别名:
b-ht933;Nsc310831;Azepexole hydrochloride;B-HT 933 (hydrochloride);Azepexole dihydrochloride;β2AR/M3-receptor agonist-1;B-HT 933 DIHYDROCHLORIDE SELECTIVE A2 AD RENORE;5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(dihydrochloride;5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(4,5-d)azepin-2-aminedihydrochloride;2-amino-6-ethyl-4,5,7,8-tetrahydro-6h-oxazolo(5,4-d)azepinedihydrochloride
CBNumber:
CB9496972
化学式:
C9H16ClN3O
分子量:
217.7
MOL File:
36067-72-8.mol

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 物理性質

貯蔵温度 :
Desiccate at RT
溶解性:
H2O: >20 mg/mL
外見 :
個体
色:
ホワイトからオフホワイト

安全性情報

WGK Germany  2
RTECS 番号 RQ5831345

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC2758
B-HT 933 dihydrochloride
36067-72-8 10mg ¥67000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC2758
B-HT 933 dihydrochloride
36067-72-8 50mg ¥284000 2024-03-01 購入

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 化学特性,用途語,生産方法

説明

B-HT 933 is an agonist of α2-adrenergic receptors (α2-ARs) with an EC50 value of 0.65 μM for contraction of canine sapheneous veins. It induces concentration-dependent inhibition of the twitch response in rat vas deferens and guinea pig ileum. B-HT 933 induces sedation and reduces motor activity in mice, an effect that is reversed by the α2-AR antagonist yohimbine . B-HT 933 decreases blood pressure and cardiac output in cats injected with 30 μg/kg intracisternally. It also exhibits antinociceptive effects in mice with ED50 values of 12.5, 20.5, and 6.1 mg/kg for the tail-immersion, tail-pinch, and acetic acid writhing tests, respectively.

使用

B-HT 933 Dihydrochloride is a selective α2-adrenoceptor agonist and has less potent inhibitory effect on the sympathetic vasopressor responses in diabetic rats.

6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 上流と下流の製品情報

原材料

準備製品


6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩 生産企業

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36067-72-8(6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩)キーワード:


  • 36067-72-8
  • 2-amino-6-ethyl-4,5,7,8-tetrahydro-6h-oxazolo(5,4-d)azepinedihydrochloride
  • 5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(4,5-d)azepin-2-aminedihydrochloride
  • 5-d)azepin-2-amine,5,6,7,8-tetrahydro-6-ethyl-4h-oxazolo(dihydrochloride
  • b-ht933
  • B-HT 933 DIHYDROCHLORIDE SELECTIVE A2 AD RENORE
  • Azepexole dihydrochloride, 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride
  • Azepexole hydrochloride
  • Nsc310831
  • Azepexole dihydrochloride
  • B-HT 933 (hydrochloride)
  • β2AR/M3-receptor agonist-1
  • 6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン·2塩酸塩
  • B-HT-933
  • 6-エチル-5,6,7,8-テトラヒドロ-4H-オキサゾロ[4,5-d]アゼピン-2-アミン・2塩酸塩
  • αアドレナリン作動薬
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