Exendin-3 (9-39) amide

Exendin-3 (9-39) amide 구조식 이미지
카스 번호:
133514-43-9
상품명:
Exendin-3 (9-39) amide
동의어(영문):
EXENDIN (9-39);EXENDIN 3 (9-39);Exendin-4 (9-39);Hexanal Impurity 5;EXENDIN (9-39) AMIDE;EXENDIN FRAGMENT 9-39;EXENDIN-3 (9-39) AMIDE;EXENDIN [9-39] PEPTIDE;Exendin (9-39) Acetate;Exendin 4 (9-39) amide
CBNumber:
CB0109941
분자식:
C149H234N40O47S
포뮬러 무게:
3369.76
MOL 파일:
133514-43-9.mol
MSDS 파일:
SDS

Exendin-3 (9-39) amide 속성

밀도
1.51
RTECS 번호
LF2460000
저장 조건
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
H2O : 50 mg/mL (14.84 mM; Need ultrasonic)
물리적 상태
고체
물리적 상태
단단한 모양
색상
Off-white to pale purple
수용성
1mg/ml로 물에 용해됨
InChIKey
WSEVKKHALHSUMB-UHFFFAOYSA-N

안전

WGK 독일 3

Exendin-3 (9-39) amide C화학적 특성, 용도, 생산

개요

Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats.

용도

Biological probe.

일반 설명

Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin.

Exendin-3 (9-39) amide 준비 용품 및 원자재

원자재

준비 용품


Exendin-3 (9-39) amide 공급 업체

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