자일로푸라민

자일로푸라민
자일로푸라민 구조식 이미지
카스 번호:
3563-92-6
한글명:
자일로푸라민
동의어(한글):
자일로푸라민
상품명:
Zylofuramine
동의어(영문):
Zylofuramine;(1R)-N-ethyl-1-[(2R)-oxolan-2-yl]-2-phenylethanamine;(1R)-N-ethyl-1-[(2R)-oxolan-2-yl]-2-phenyl-ethanamine;ethyl-[(1R)-2-phenyl-1-[(2R)-tetrahydrofuran-2-yl]ethyl]amine;2-Furanmethanamine, N-ethyltetrahydro-α-(phenylmethyl)-, [R-(R*,R*)]- (9CI)
CBNumber:
CB01180114
분자식:
C14H21NO
포뮬러 무게:
219.32
MOL 파일:
3563-92-6.mol

자일로푸라민 속성

끓는 점
328.8±15.0 °C(Predicted)
밀도
1.3277 (rough estimate)
굴절률
1.5240 (estimate)
저장 조건
Store at -20°C
용해도
DMSO: ≥ 100 mg/mL (455.95 mM)
물리적 상태
Solid
산도 계수 (pKa)
9.35±0.19(Predicted)
색상
White to off-white

안전

독성 LD50 oral in mouse: 475mg/kg

자일로푸라민 C화학적 특성, 용도, 생산

Originator

Zylofuramine,ZYF Pharm Chemical

Manufacturing Process

A mixture of furfurylbenzyl ketone and of N-ethyl-α-benzylamine in methanol was hydrogenated over Raney nickel at 150°C and at a pressure of 1500 p.s.i. The catalyst was removed by filtration and the solvent removed by vacuum distillation. The oily residue was taken up in ether, the ether solution washed with dilute hydrochloric acid and the aqueous layer separated. Addition of 35% sodium solution caused the separation of an oil which was taken up in ether. Removal of the ether by evaporation followed by distillation of the residue gave N-ethyl-α-benzyltetrahydrofurfurylamine, boillin point 101°C/0.07 mm.

Therapeutic Function

Psycho-analeptic

자일로푸라민 준비 용품 및 원자재

원자재

준비 용품


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