6-클로로(1H)인다졸

6-클로로(1H)인다졸
6-클로로(1H)인다졸 구조식 이미지
카스 번호:
698-25-9
한글명:
6-클로로(1H)인다졸
동의어(한글):
6-클로로(1H)인다졸
상품명:
6-Chloro-1H-indazole
동의어(영문):
6-CHLOROINDAZOLE;BUTTPARK 121\04-74;6-CHLORO (1H)INDAZOLE;1H-Indazole, 6-chloro-;6-Chloro-1H-indazole, >95%;6-chloro-1H-indazole(WXC03625)
CBNumber:
CB0120070
분자식:
C7H5ClN2
포뮬러 무게:
152.58
MOL 파일:
698-25-9.mol
MSDS 파일:
SDS

6-클로로(1H)인다졸 속성

녹는점
174-177℃
끓는 점
309.5±15.0 °C(Predicted)
밀도
1.425±0.06 g/cm3(Predicted)
저장 조건
Sealed in dry,Room Temperature
산도 계수 (pKa)
12.82±0.40(Predicted)
InChI
InChI=1S/C7H5ClN2/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,(H,9,10)
InChIKey
VUZQHUVRBPILAX-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC(Cl)=C2)C=N1
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 22
HS 번호 2933998090
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P330 입을 씻어내시오.

6-클로로(1H)인다졸 C화학적 특성, 용도, 생산

주요 응용

6-Chloro-1H-indazole is a useful research chemical.

Research

Indazoles are an essential class of heterocyclic compounds with many applications as biological and pharmaceutic agents. They have been extensively studied due to their interesting chemical and biological characteristics. Indazole belongs to the azoles family, which includes carbon, hydrogen and a nitrogen atom. Indazole has a heterocyclic structure made up of benzene and pyrazole rings. Indazole derivatives have a wide range of biological activities. For instance, indazole derivatives show vasorelaxant and anti-aggregator activities by stimulating NO release and increasing cGMP levels. K?ksal et al. investigated the in vitro inhibitory effects of some indazole derivatives. The inhibitory effects of molecules on enzyme activity were tested in vitro; Ki values were calculated using Lineweaver-Burk diagrams. Ki values were found as 252.78 ± 27.85 mM for 6-Chloro-1H-indazole. The results indicated that the indazole molecules had effective LPO inhibition. According to the results, the 6-Bromo-1H-indazole molecule had the strongest inhibitory effect, whereas the 6-Chloro-1H-indazole had the weakest inhibitory effect[1].

6-클로로(1H)인다졸 준비 용품 및 원자재

원자재

준비 용품


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