메틸티오글라이콜레이트
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메틸티오글라이콜레이트 속성
- 녹는점
- -24 °C
- 끓는 점
- 42-43 °C/10 mmHg (lit.)
- 밀도
- 1.187 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.466(lit.)
- 인화점
- 86 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 40g/L
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 8.04±0.10(Predicted)
- 색상
- 무색의
- 수용성
- 40g/L(20℃)
- 감도
- Air Sensitive
- BRN
- 506259
- InChIKey
- MKIJJIMOAABWGF-UHFFFAOYSA-N
- CAS 데이터베이스
- 2365-48-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,T | ||
---|---|---|---|
위험 카페고리 넘버 | 10-20/22-36/37/38-25 | ||
안전지침서 | 26-36/37-45-36/37/39-28A | ||
유엔번호(UN No.) | UN 1992 3/PG 3 | ||
WGK 독일 | 1 | ||
RTECS 번호 | AI7350000 | ||
TSCA | Yes | ||
위험 등급 | 3 | ||
포장분류 | III | ||
HS 번호 | 29309070 | ||
유해 물질 데이터 | 2365-48-2(Hazardous Substances Data) | ||
독성 | mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689, |
메틸티오글라이콜레이트 C화학적 특성, 용도, 생산
화학적 성질
CLEAR COLOURLESS LIQUID용도
Methyl Thioglycolate is an derivative of Thioglycolic Acid (T350760), an organic compound containing both a thiol and a carboxylic acid functional groups. Thioglycolic Acid and its derivatives are oft en used in organic synthesis as a nucleophile in thioglycolysis reactions and is also used as a S transfer agent for sulfonyl chloride synthesis. Methyl Thioglycolate have been studied for the its inf luence on neocarzinostatin activation and expression of DNA damage.생산 방법
Adding thioglycollic acid with purity of between 70.0 and 96.0 percent and methanol with purity of between 95.0 and 99.9 percent into a reaction device according to the molar ratio of 1:1.3-4.0; subsequently, adding an activating agent into the reaction device, stirring and heating for reaction; and after the reaction is finished, carrying out separatory distillation on reaction products to obtain the methyl thioglycolate. The activating agent is a p-toluenesulfonic acid methanol solution with a mass concentration of between 20 and 30 percent, and the use amount is 0.5 to 1.0 percent of the total mass of relative input materials.주요 응용
Methyl thioglycolate is a chemical compound that is used in the pharmaceutical industry as an intermediate. It has been used to synthesize anti-inflammatory drugs, such as aspirin and ibuprofen, and also for the treatment of autoimmune diseases. Methyl thioglycolate binds to amino acids on the surface of bacteria, which prevents them from functioning properly. This binding causes the cells to stop growing and die.일반 설명
Methyl thioglycolate reacts with nonprotein component of the antitumor antibiotic neocarzinostatin to form 1:1 adduct. It reacts with isothiocyanate to form Rhodanine.메틸티오글라이콜레이트 준비 용품 및 원자재
원자재
준비 용품
Methyl 3-amino-4-methylthiophene-2-carboxylate
메틸3-클로로-4-메틸티오펜-2-카르복실레이트
METHYL 3-AMINO-6-METHYLTHIOPHENO[2,3-B]PYRIDINE-2-CARBOXYLATE
5-클로로-4-메톡시티오펜-3-카르복실산
3-AMINO-6-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
메틸3-아미노-4-페닐티오펜-2-카르복실레이트
5-클로로-4-메톡시티오펜-3-카르보닐염화물
Methyl 4-oxotetrahydrothiophene-3-carboxylate
5-브로모-4-메톡시티오펜-3-카복실산
3-아미노-4,5,6,7-테트라하이드로-벤조[B]티오펜-2-카복시산메틸에스테르
로다닌-3-아세트산
3-AMINOTHIOPHENE-2-CARBOXAMIDE
디메틸4-아미노티오펜-2,3-디카르복실레이트염산염
Methyl 3-amino-2-thiophenecarboxylate
3-클로로-4-메틸-2-티오펜카르복실산
메틸3-클로로티오펜-2-카복실레이트
Methyl 3-hydroxythiophene-2-carboxylate
S-Methyl isovalerate
4-메틸-3-아미노-2-(메톡시카르보닐)-4,5-디히드로티오펜
1-Benzothiophen-5-amine
메틸3-아미노-5-(tert-부틸)티오펜-2-카르복실레이트
티펜술퍼론-메틸
5-브로모-4-메톡시티오펜-3-카보닐클로라이드
4-메톡시티오펜-3-카르복사미드
4-메톡시티오펜-3-카르복실산
4-Chlorothieno[3,2-d]pyrimidine
3-아미노-5-(TERT-부틸)티오펜-2-카르복스아미드
METHYL 4-METHOXYTHIOPHENE-3-CARBOXYLATE
5-니트로-1-벤조티오펜-2-카르복실산
METHYL 7-AMINOTHIENO[2,3-B]PYRAZINE-6-CARBOXYLATE
메틸티오글라이콜레이트 공급 업체
글로벌( 405)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Qingdao Zhongke Huatai Industrail Co., Ltd. | +86-532-86898076 +86-15153292017 |
zkhtchem@163.com | China | 25 | 58 |
Jinan Qinmu Fine Chemical Co.,Ltd. | +8618660799346 |
sales@qinmuchem.com | China | 1009 | 58 |
Qingdao RENAS Polymer Material Co., Ltd. | +86-0532-86867058 +86-18562606086 |
sales@qdrenas.com | China | 328 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5895 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 |
sales06@hbduling.cn | China | 8054 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20291 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@sdzhonghuimaterial.com | China | 983 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |