ChemicalBook >제품 카탈로그 >Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like 구조식 이미지
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상품명:
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like
동의어(영문):
Anti-ATG5 (C-terminal) antibody produced in rabbit;Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like 속성
저장 조건
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안전
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like C화학적 특성, 용도, 생산
용도
Rabbit anti-ATG5 (C-terminal) antibody has been used for western blot analysis in U2OS cells. The antibody has also been used for immunoblot assays in CT26 and MCA205 cells.
일반 설명
Macroautophagy, usually referred to as autophagy, is a major pathway for bulk degradation of cytoplasmic constituents and organelles. Autophagy is an evolutionary conserved pathway seen in all eukaryotic cells. At least 16 ATG genes, required for autophagosome formation were identified in yeast by genetic screens. For many of these genes, related homologs have been identified in mammals. Atg5, also known as Apg5, is a 32 kDa protein essential for autophagy. Atg5 is covalently modified by Atg12, a ubiquitin-like modifier. This conjugation reaction requires ATP and two enzymes, Atg7 and Atg10, which are E1- and E2-like enzymes, respectively. The Atg12-Atg5 conjugate interacts non-covalently with Atg16. The Atg12-Atg5-Atg16 complex localizes to autophagosome precursors and plays an essential role in autophagosome formation. It has been reported that in addition to the role of Atg5 in the formation of autophagosomes, an Atg5 fragment produced by calpain cleavage has pro-apoptotic properties.
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like 준비 용품 및 원자재
원자재
준비 용품
Anti-Apg5, Anti-Apg5L, Anti-Apoptosis-specific protein, Anti-ASP, Anti-Atg5 (C-terminal) antibody produced in rabbit, Anti-Autophagy protein 5-like 공급 업체
