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베마칼란트 C화학적 특성, 용도, 생산
개요
Vernakalant is a potassium channel blocker that was approved in
Europe in 2010 for treatment of atrial fibrillation (AF), a condition of
cardiac arrhythmia in which the atria of the heart beat irregularly due to
changes in cardiac ion channel function and distribution.
Vernakalant has activity for cardiac Na+ and K+ channels and also for the
atrial-selective Kv1.5 channel. Vernakalant (RSD1235) was characterized
in animal models to assess efficacy, atrial selectivity, and reduction in side effects.
