Sofosbuvir IMpurity B

Sofosbuvir IMpurity B 구조식 이미지
카스 번호:
1496552-51-2
상품명:
Sofosbuvir IMpurity B
동의어(영문):
Sofosbuvir impurity K;Sofosbuvir IMpurity B;Sofosbuvir Chloro Analog;Sofosbuvir Chloro Analogue;sofosbuvir impurity Y008005-K;L-Alanine, N-[[P(S),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-chloro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;(2S)-isopropyl 2-(((((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
CBNumber:
CB02716563
분자식:
C22H29ClN3O9P
포뮬러 무게:
545.91
MOL 파일:
1496552-51-2.mol

Sofosbuvir IMpurity B 속성

밀도
1.43±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
Solid
산도 계수 (pKa)
9.39±0.10(Predicted)
색상
Light yellow to yellow

안전

Sofosbuvir IMpurity B C화학적 특성, 용도, 생산

용도

Chloro Sofosbuvir is an impurity of Sofosbuvir (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity B 준비 용품 및 원자재

원자재

준비 용품


Sofosbuvir IMpurity B 공급 업체

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