CP 94253 hydrochloride

CP 94253 hydrochloride C화학적 특성, 용도, 생산

개요

CP 94,253 is an agonist of the serotonin (5-HT) receptor subtype 5-HT_1B (K_i = 2 nM in a radioligand binding assay). It is selective for 5-HT_1B over 5-HT_1A, 5-HT_1D, 5-HT_1C, and 5-HT₂ receptors (K_is = 89, 49, 860, and 1,600 nM, respectively). CP 94,253 (10 and 17 mg/kg) reduces aggressive behavior in a resident-intruder test in mice, as well as decreases alcohol-induced aggression in mice with an ED₅₀ value of 3.8 mg/kg. It decreases the time mice spend immobile in the forced swim test by 43%, indicating antidepressant-like activity, when administered at a dose of 5 mg/kg. CP 94,253 (2.5 mg/kg) also increases drinking in the Vogel punished drinking task, indicating anxiolytic-like activity, in rats.

용도

CP 94253 Hydrochloride is a potent and selective serotonin 5-HT1B receptor agonist with anticonvulsant activity.

CP 94253 hydrochloride 준비 용품 및 원자재

원자재

준비 용품

CP 94253 hydrochloride 공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9602	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Maiev Biotech Co.,Ltd	18852558852	maievbiotech2@163.com	China	79	58
Anqing YanZhi Pharma Discovery Co.,Ltd.	18055651951	2272561977@qq.com	China	321	58
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9612	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4287	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58