ZSTK474

ZSTK474 구조식 이미지
카스 번호:
475110-96-4
상품명:
ZSTK474
동의어(영문):
CS-438;ZSTK 474;ZSTK474 BASE;ZSTK474/ZSTK-474;ZSTK474 USP/EP/BP;2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine;2-(DifluoroMethyl)-1-[4,6-di(4-Morpholinyl)-1,3,5-triazin-2-yl]-1H-benziMidaz;1-[BIS(MORPHOLIN-4-YL)-1,3,5-TRIAZIN-2-YL]-2-(DIFLUOROMETHYL)-1,3-BENZODIAZOLE;2-(difluoromethyl)-1-(4,6-dimorpholino-1,3,5-triazin-2-yl)-1H-benzo[d]imidazole;ZSTK 474 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine
CBNumber:
CB0505419
분자식:
C19H21F2N7O2
포뮬러 무게:
417.41
MOL 파일:
475110-96-4.mol
MSDS 파일:
SDS

ZSTK474 속성

녹는점
217-219 °C(Solv: ethanol (64-17-5))
끓는 점
640.3±65.0 °C(Predicted)
밀도
1.57
저장 조건
-20°C
용해도
DMSO(최대 20mg/ml) 또는 에탄올(가온 시 최대 2.5mg/ml)에 용해됩니다.
물리적 상태
백색 분말.
산도 계수 (pKa)
5.21±0.10(Predicted)
색상
흰색 또는 황백색
안정성
제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.

안전

HS 번호 29349990

ZSTK474 C화학적 특성, 용도, 생산

용도

ZSTK474 is a triazine derivative that acts as an inhibitor of class I phosphatidylinositol 3-kinase (PI3K) isoforms (IC50s = 17, 53, and 6 nM for p110β, -γ, and -δ, respectively). It is selective for PI3K, as it has negligible activity against 139 other kinases when tested at 30 μM. ZSTK474 is orally bioavailable and shows strong antitumor activity against human cancer xenografts in mice. The efficacy of ZSTK474 against certain cancer cells and tumors can be enhanced by combination therapy.

정의

ChEBI: A triamino-1,3,5-triazine that is 1,3,5-triazine in which two of the hydrogens have been replaced by morpholin-4-yl groups while the third hydrogen has been replaced by a 2-(difluoromethyl)benzimidazol-1-yl group. It is an inhibitor of phosphatidylinositol 3-kinase.

ZSTK474 준비 용품 및 원자재

원자재

준비 용품


ZSTK474 공급 업체

글로벌( 157)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32956 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22787 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com China 52849 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58

Copyright 2019 © ChemicalBook. All rights reserved