3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&

3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& 구조식 이미지
카스 번호:
345957-19-9
상품명:
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&
동의어(영문):
Liothyronine sodium hydrate;3,3',5-Triiodo-L-thyronine (sodium salt hydrate);3,3μ,5-Triiodo-L-thyronine hydrate sodium salt;3,3',5-Triiodo-L-thyronine sodium salt hydrate 95%;3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& USP/EP/BP;Sodium(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoatehydrate(1:1:1)
CBNumber:
CB0505510
분자식:
C15H11I3NO4Na
포뮬러 무게:
672.96
MOL 파일:
345957-19-9.mol

3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& 속성

녹는점
205 °C (dec.)(lit.)
저장 조건
Store at -20°C
용해도
DMF: 0.25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 1 mg/ml
물리적 상태
결정성 고체
optical activity
[α]22/D +21.5°, c = 2 in 1 N HCl: ethanol, 1:2

안전

안전지침서 22-24/25
WGK 독일 3

3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& C화학적 특성, 용도, 생산

개요

3,3'',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5''-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling. It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 μM.

3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& 준비 용품 및 원자재

원자재

준비 용품


3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& 공급 업체

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