Human Menopausal Gonadotrophin
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Human Menopausal Gonadotrophin 속성
- 저장 조건
- 2-8°C
- InChI
- InChI=1S/C9H18O/c1-9(2,3)7-5-4-6-8-10/h8H,4-7H2,1-3H3
- InChIKey
- CBUWTGCATVNMJE-UHFFFAOYSA-N
- SMILES
- C(=O)CCCCC(C)(C)C
- CAS 데이터베이스
- 61489-71-2(CAS DataBase Reference)
안전
위험품 표기 | B | ||
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WGK 독일 | 3 | ||
RTECS 번호 | MT6425640 |
Human Menopausal Gonadotrophin C화학적 특성, 용도, 생산
개요
Human Menopausal Gonadotrophin (HMG), also known as Menotropins, is a combination of FSH and LH extracted from the urine of postmenopausal women at a ratio of 1 : 1. HMG is a gonadotropin administered by intramuscular or subcutaneous injection for the treatment of infertility in women or men.용도
Gonad-stimulating principle.일반 설명
Pituitary hormones prepared from the urine of postmenopausalwomen whose ovarian tissue does not respondto gonadotropin are available for medicinal use as theproduct menotropins (Pergonal). The latter has FSH andLH gonadotropin activity in a 1:1 ratio. Menotropins areuseful in the treatment of anovular women whose ovariesrespond to pituitary gonadotropins but who have a gonadotropindeficiency caused by either pituitary or hypothalamusmalfunction. Usually, menotropins are administeredintramuscularly in an initial dose of 75 IU of FSHand 75 IU of LH daily for 9 to 12 days, followed by 10,000IU of chorionic gonadotropin 1 day after the last dose ofmenotropins.Mechanism of action
Human menopausal gonadotropin (HMG), which contains follicle-stimulating hormone (FSH) and luteinizing hormone (LH), can secrete gonadotropin to promote follicle maturation to stimulate ovulation and accelerate the development of corpus luteum.HMG is derived from the urine of postmenopausal women[1].Clinical Use
Menotropins are a natural product that is obtained from the urine of postmenopausal women and then biologically standardized (international units [IU]) for FSH and LH activities in an approximate ratio of 1:1. Menotropins are used in males with primary (hypothalamic) or secondary (pituitary) hypogonadism to stimulate spermatogenesis, providing they have been treated previously with human chorionic gonadotropin (hCG; a peptide hormone of placental origin that has activity very similar to LH) to effect masculinization (increased testosterone inducing ovulation in women who are having difficulty ovulating as a result of either hypothalamic or pituitary hormonal dysfunction. The menotropins are given for 7 to 12 days, and after clinical evaluation (via ultrasound) indicates the presence of a mature follicle, a single dose of hCG is given to simulate the typical LH surge that normally triggers ovulation. Also, women use the combination of menotropins and hCG to promote the development of multiple follicles when they are participating in an IVF program requiring the recruitment of follicles.부작용
Side effects: Headache, mild stomach pain/bloating, redness/pain at the injection site, breast tenderness, or dizziness may occur.Serious side effects, including: vaginal bleeding, flu-like symptoms (such as fever, chills, joint pain, muscle ache, tiredness).
Human Menopausal Gonadotrophin 준비 용품 및 원자재
원자재
준비 용품
Human Menopausal Gonadotrophin 공급 업체
글로벌( 126)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 |
wrjmoon2000@163.com | China | 264 | 58 |
Strong peptide cross-border e-commerce Co. LTD | +undefined13930052870 |
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Qingdao Xinli Technology Development Co., Ltd. | +8616632313095 |
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admin@guyunchem.com | China | 616 | 58 |
Sigma Audley | +86-18336680971 +86-18126314766 |
nova@sh-teruiop.com | China | 497 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 |
admin@oudaxin.com | China | 114 | 58 |
Hebei Kangcang new material Technology Co., LTD | +8615713292910 |
Nancy@kangcang.com.cn | China | 341 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 973 | 58 |
CONTIDE BIOTECH CO.,LTD | +852-53358525 |
xena@healthtide-api.com | China | 587 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
Human Menopausal Gonadotrophin 관련 검색:
아세틸아세토산 제2철 디스프로슘 트리(2,2,6,6-테트라메틸-3,5-헵탄디오네이트) 코발트(II) 아세틸아세토네이트 하이드레이트 아세틸아세톤산 구리 실버 아세틸아세토네이트 알루미늄 아세틸아세토네이트
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
PHENYLSELENOL
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
TERT-BUTYL ISOCYANIDE
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
METHYL ISOCYANOACETATE
Ethyl isocyanoacetate
N-BUTYLISOCYANIDE
Tosylmethyl isocyanide
SALCOMINE
Benzyl isocyanide
Tris(2,4-pentanedionato)chroMiuM(III)