N-아세틸-4-벤조퀴논이민
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N-아세틸-4-벤조퀴논이민 속성
- 녹는점
- 74-75
- 끓는 점
- 255.6±43.0 °C(Predicted)
- 밀도
- 1.13±0.1 g/cm3(Predicted)
- 저장 조건
- -70°C
- 용해도
- 클로로포름(약간 용해됨, 초음파 처리), DMSO(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- -3.37±0.20(Predicted)
- 색상
- 옅은 노란색에서 매우 어두운 빨간색까지
- 안정성
- 온도, 수분, 빛 및 산소에 민감함
- CAS 데이터베이스
- 50700-49-7
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
---|---|---|---|
RTECS 번호 | AC6960000 | ||
HS 번호 | 2902110000 | ||
독성 | LD50 i.p. in male BALB/c mice: 20 mg/kg (Dahlin, Nelson) |
N-아세틸-4-벤조퀴논이민 C화학적 특성, 용도, 생산
개요
N-화학적 성질
Yellow Crystalline Solid용도
N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses. At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.N-아세틸-4-벤조퀴논이민 준비 용품 및 원자재
원자재
준비 용품
N-아세틸-4-벤조퀴논이민 공급 업체
글로벌( 84)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14336 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 |
1015@dideu.com | China | 2613 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 |
overseasales@yongstandards.com | China | 11927 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 |
info@hanhongsci.com | China | 42981 | 64 |
N-아세틸-4-벤조퀴논이민 관련 검색:
DL-NORPHENYLEPHRINE HYDROCHLORIDE
1,2,3,4-Tetrahydro-4,8-dihydroxy-2-methyl-isoquinoline
DL-NORPHENYLEPHRINE HYDROCHLORIDE
Phenylephrine O-Aryl Sulfate
Phenylephrine Impurity 32
Phenylephrine hydrochloride
Phenylephrine USP RC G
N-Acetylphenylephrine
2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
(R)-(-)-Phenylephrine-d3 HCl
1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
benzyl(3-hydroxyphenacyl)methylammonium chloride
Phenylephrine EP Impurity D
Phenylephrine EP Impurity D
3-Hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]MethylaMino]-4-oxo-butanoic Acid
1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline
N-(2-Succinyl) Phenylephrine
Phenylephrine Impurity 33