CGP 55845

CGP 55845 구조식 이미지
카스 번호:
149184-22-5
상품명:
CGP 55845
동의어(영문):
CGP 55845;CGP 55845 hydrochlor;CGP 55845 hydrochloride;benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;(2S)-3-[[(1S)-1-(3,4-DICHLOROPHENYL)ETHYL]AMINO-2-HYDROXYPROPYL](PHENYLMETHYL)PHOSPHINIC ACID;(2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinicacidhydrochloride
CBNumber:
CB0718390
분자식:
C18H23Cl3NO3P
포뮬러 무게:
438.71
MOL 파일:
149184-22-5.mol
MSDS 파일:
SDS

CGP 55845 속성

저장 조건
room temp
용해도
DMSO: 용해성5mg/mL, 투명(가온)
물리적 상태
가루
색상
흰색에서 베이지색

안전

WGK 독일 3
RTECS 번호 SZ4680000

CGP 55845 C화학적 특성, 용도, 생산

용도

CGP is a potent, selectie GABAB receptor antagonist.

생물학적 활성

Potent, selective GABA B receptor antagonist (IC 50 = 5 nM) that prevents agonist binding (pK i = 8.35) and inhibits GABA and glutamate release (pEC 50 values are 8.08 and 7.85 respectively). Inhibits GABA B responses to baclofen (IC 50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro .

Biochem/physiol Actions

CGP 55845 is a potent selective GABA-B receptor antagonist with an IC50 of 5 nM.

CGP 55845 준비 용품 및 원자재

원자재

준비 용품


CGP 55845 공급 업체

글로벌( 24)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
BOC Sciences --
info@bocsci.com USA 0 65
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44843 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Shanghai Universal Biotech Co.,Ltd 18768175414
gaojun@univ-bio.com China 24998 58
Xi'an Qiyue Biotechnology Co., Ltd. 400-400-6966-012-012 17778955912
2957605606@qq.com China 2535 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 23963 58

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