4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID 구조식 이미지
카스 번호:
23918-98-1
상품명:
4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID
동의어(영문):
AA-307;Lentysine;lentinacin;eritadenine;D-ERITADENINE;d-erythronicaci;4-(6-AMinopurin-9-yl)-4-deoxy-D-erythronic Acid;4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID;d-4-(6-amino-9h-purin-9-yl)-4-deoxyerythronicacid;4-(6-AMino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid
CBNumber:
CB0759223
분자식:
C9H11N5O4
포뮬러 무게:
253.22
MOL 파일:
23918-98-1.mol

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID 속성

녹는점
>270°C (dec.)
끓는 점
721℃
알파
D +51.4° (c = 1.6 in 0.1N NaOH)
밀도
1.92
굴절률
1.7610 (estimate)
인화점
390℃
저장 조건
Refrigerator
용해도
Aqueous Acid (Slightly, Heated), DMSO (Slightly)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
3.37±0.17(Predicted)
색상
흰색~밝은 베이지

안전

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID C화학적 특성, 용도, 생산

개요

The empirical formula of this alkaloid should read C9H II N 504' The natural compound is the D-Erythro-form of the base. Melting points recorded for this alkaloid are 279°C (dec.) by Kamiya et al and 26l-3°C (dec.) by Chibata and his colleagues. The alkaloid has specific rotations of [α]D+ 16° (N-HC1) and [α] D + 50° (0.1 N-NaOH). It gives an ultraviolet spectrum in H20 with a single absorption maximum at 26l.5 nm which is shifted to 259.5 nm inN-HCl and is at 262 nm in N-NaOH. Eritadenine forms a methyl ester, m.p. 231°C (dec.) and a diacetate, m.p. 225°C (dec.).

화학적 성질

Pale Yellow Solid

용도

Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.

참고 문헌

Chibata et al., Experientia, 25,1237 (1969)
Kamiya et al., Tetrahedron Lett., 4729 (1969)

4-(9-ADENYL)-D-ERYTHRO-2,3-DIHYDROXYBUTYRIC ACID 준비 용품 및 원자재

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