NECA
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NECA 속성
- 녹는점
- 229-231°C
- 밀도
- 1.87±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- 45%(w/v) aq 2-하이드록시프로필-β-사이클로덱스트린: 0.2mg/mL 용액은 4℃에서 며칠 동안 보관할 수 있습니다.
- 산도 계수 (pKa)
- 12.93±0.70(Predicted)
- 물리적 상태
- 가루
- 색상
- 하얀색
- 안정성
- 흡습성
- InChIKey
- JADDQZYHOWSFJD-FLNNQWSLSA-N
- CAS 데이터베이스
- 35920-39-9
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T+ | ||
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위험 카페고리 넘버 | 28 | ||
안전지침서 | 22-26-36-45 | ||
유엔번호(UN No.) | UN 2811 6.1/PG 2 | ||
WGK 독일 | 3 | ||
RTECS 번호 | VJ2232000 | ||
위험 등급 | 6.1(a) | ||
포장분류 | I | ||
HS 번호 | 29349990 |
그림문자(GHS): | |||||||||||||||
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신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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NECA C화학적 특성, 용도, 생산
화학적 성질
White Solid용도
A potent adenosine receptor agonist. Inhibits platelet aggregation and is centrally active in vivo정의
ChEBI: A derivative of adenosine in which the 5'-hydroxymethyl group is replaced by an N-ethylcarboxamido group.일반 설명
A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14 nM, 20 nM, 2.4 μM and 6.2 nM for A1, A2A, A2B, A3, respectively). Increases intracellular cAMP production (EC50 = 3.1 μM in A2B expressing CHO cells). Shown to increase glucagon release in a dose-dependent manner and inhibit insulin release at low concentrations. Although at higher concentration some insulin release is observed. Also, displays a wide range adenosine-dependent effects, such as blocking platelet aggregation and inhibiting DNA synthesis. When administered at reperfusion, it is shown reduce infarction and block the formation of the mitochondrial permeability transition pore by activating p70S6 kinase.생물학적 활성
Potent adenosine receptor agonist (K i values are 14, 20 and 6.2 nM for human A 1 , A 2A and A 3 receptors respectively; EC 50 = 2.4 μ M for human A 2B ). Inhibits platelet aggregation and is centrally active in vivo .NECA 준비 용품 및 원자재
원자재
준비 용품
NECA 공급 업체
글로벌( 101)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29898 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
TopScience Biochemical | 00852-68527855 |
info@itopbiochem.com | China Hong Kong | 902 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24822 | 58 |
NewCan Biotech Limited | +86-0571-86912261 +8613735419629 |
sales@newcanbio.com | China | 9980 | 58 |
Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 |
sales@dogechemical.com | China | 4128 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
NECA 관련 검색:
he-neca
2-IODO-NECA
5'-EthylcarboxaMido-2',3'-isopropylidene Adenosine
2-Chloro-NECA
NECA 5'-N-[ADENINE-2,8-3H]-
N6-BENZYL-NECA
CGS 21680, [CARBOXYETHYL-3H(N)]-
2-CHLORO-2',3'-O-ISOPROPYLIDENEADENOSINE-5'-N-ETHYLCARBOXAMIDE
EB-47 DIHYDROCHLORIDE DIHYDRATE
CGS 21680
NECA
5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE
DANSYL-NECA
5'-N-ETHYLCARBOXAMIDOADENOSINE, [ADENINE-2,8-3H]-
CGS-21680 HYDROCHLORIDE