AL-8810
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AL-8810 속성
- 끓는 점
- 594.6±50.0 °C(Predicted)
- 밀도
- 1.21±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 10mg/mL, 가용성
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 4.76±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
안전
WGK 독일 | 3 |
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AL-8810 C화학적 특성, 용도, 생산
용도
AL 8810 is an 11β-fluoro analog of PGF2α which acts as a potent and selective antagonist at the FP receptor. AL 8810 has weak intrinsic agonist activity on FP receptor preparations in the 200-300 nM range, yet it fully antagonizes the activity of the potent FP receptor agonist fluprostenol at this concentration, with EC50 values of approximately 430 nM. AL 8810 fully antagonized the bimatoprost-induced calcium mobilization in Swiss 3T3 fibroblasts at 100 μM, indicating that bimatoprost acts as an FP agonist in this preparation. The Ki for the inhibition of several potent agonists at the cloned human ciliary body FP receptor is in the range of 1-2 μM.Biochem/physiol Actions
AL-8810 is a novel prostaglandin F2α analog; selective FP prostanoid receptor antagonist.AL-8810 준비 용품 및 원자재
원자재
준비 용품
AL-8810 공급 업체
글로벌( 35)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30253 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4428 | 55 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9708 | 58 |
Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 |
synstar518@163.com | China | 1991 | 58 |
BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44843 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |