(5-페닐-2-우레이도)티오펜-3-카복스아마이드

(5-페닐-2-우레이도)티오펜-3-카복스아마이드
(5-페닐-2-우레이도)티오펜-3-카복스아마이드 구조식 이미지
카스 번호:
354811-10-2
한글명:
(5-페닐-2-우레이도)티오펜-3-카복스아마이드
동의어(한글):
(5-페닐-2-우레이도)티오펜-3-카복스아마이드
상품명:
(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE
동의어(영문):
IKK2-IN-4;IKK-2 INHIBITOR VI;IKK2 Inhibitor VI,IKK-2 Inhibitor VI;(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE;5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide;2-(carbamoylamino)-5-phenylthiophene-3-carboxamide;2-[(AMinocarbonyl)aMino]-5-phenyl-3-thiophenecarboxaMide;3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-phenyl-;5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide|||IKK2 Inhibitor IV
CBNumber:
CB0789277
분자식:
C12H11N3O2S
포뮬러 무게:
261.3
MOL 파일:
Mol file

(5-페닐-2-우레이도)티오펜-3-카복스아마이드 속성

녹는점
>210°C (dec.)
끓는 점
445.6±45.0 °C(Predicted)
밀도
1.426±0.06 g/cm3(Predicted)
저장 조건
Refrigerator
용해도
DMSO, 메탄올(약간 용해됨)
산도 계수 (pKa)
14.00±0.70(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
라이트 베이지부터 라이트 브라운까지

안전

(5-페닐-2-우레이도)티오펜-3-카복스아마이드 C화학적 특성, 용도, 생산

개요

Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.

용도

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE is an inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.

(5-페닐-2-우레이도)티오펜-3-카복스아마이드 준비 용품 및 원자재

원자재

준비 용품


(5-페닐-2-우레이도)티오펜-3-카복스아마이드 공급 업체

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