ChemicalBook >제품 카탈로그 >(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드 구조식 이미지

카스 번호:: 171752-68-4

한글명:: (1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드

동의어(한글):: (1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드

상품명:: (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride

동의어(영문):: methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate,hydrochloride;Methyl (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride;TDF-DA-M1;Tadalafile N-2;CHEMPACIFIC 51475;Tetrahydrocarbaline;Aliskiren Impurity 65;Tadalafil Impurity 1 HCl;Tadalafil Impurity 22 HCl;Tadalafil Impurity 16 HCl

CBNumber:: CB0840958

분자식:: C20H19ClN2O4

포뮬러 무게:: 386.82886

MOL 파일:: 171752-68-4.mol

속성

안전

용도

공급 업체 230

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드 속성

녹는점: 239-241 °C

저장 조건: under inert gas (nitrogen or Argon) at 2-8°C

용해도: DMSO(약간 용해됨, 초음파 처리), 메탄올(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 황백색에서 연한 노란색

안정성: 흡습성

InChI: InChI=1/C20H18N2O4.ClH/c1-24-20(23)15-9-13-12-4-2-3-5-14(12)21-19(13)18(22-15)11-6-7-16-17(8-11)26-10-25-16;/h2-8,15,18,21-22H,9-10H2,1H3;1H/t15-,18-;/s3

InChIKey: ROYJOKDTCKPQHK-QHWQFTOMNA-N

SMILES: C12[C@@H](C3=CC=C4OCOC4=C3)N[C@H](CC=1C1C(=CC=CC=1)N2)C(OC)=O.Cl |&1:1,12,r|

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고	P264, P270, P301+P312, P330, P501
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드 C화학적 특성, 용도, 생산

제조 방법

D-tryptophan methyl ester hydrochloride and piperonal chloride dissolved in redistilled tetrahydrofuran and then added trifluoroacetic acid. Stir the reaction at 30 ° C for 10 h under the protection of nitrogen. Add sodium triacetoxyborohydride and continue the reaction for 3 hours. After the reaction is monitored by a TLC plate, the reaction solution is concentrated to about 10 mL, deionized water is added, and extracted with ethyl acetate twice. Saturated sodium chloride was washed twice, and dried under reduced pressure to obtain (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride. The yield was 86.95%, the purity was 98.76%.

(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드 준비 용품 및 원자재

원자재

준비 용품

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드 공급 업체

글로벌( 230)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3147	58
Jinan Jianfeng Chemical Co., Ltd	0531-88110457; +8615562555968	info@pharmachemm.com	China	225	58
Shandong Luning Pharmaceutical Co., Ltd.	0546-6491488 +8613305469775		China	40	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177; +8617531190177	peter@yan-xi.com	China	6011	58
Hebei Duling International Trade Co. LTD	+8617333973358	sales01@hbduling.cn	China	15442	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	985	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11012	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	sales03@chemcn.cn	China	973	58

(1R,3R)-9H-피리도[3,4-B]인돌-3-카르복실산,1,2,3,4-테트라히드로-1-(3,4-메틸렌디옥시닐),메틸에스테르,히드로클로라이드 관련 검색:

BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE] cis-ent-Tadalafil cis-Tadalafil 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile (S)-1-Boc-3-hydroxypiperidine Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- Trelagliptin succinate Tadalafil Hydroxytyrosol Benoxinate Hydrochloride Chloropretadalafil D-Tryptophan methyl ester hydrochloride (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Tadalafil EP IMpurity G Tadalafil Impurity 11 Tadalafil Impurity 39 Tadalafil Impurity 62