클로피브라이드
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클로피브라이드 속성
- 녹는점
- 34°C
- 끓는 점
- 195°C (rough estimate)
- 밀도
- 1.1635 (rough estimate)
- 굴절률
- 1.6800 (estimate)
안전
클로피브라이드 C화학적 특성, 용도, 생산
Originator
Lipenan,Charpentier,France,1974Manufacturing Process
48.5 parts of ethyl 4'-chlorophenoxyisobutyrate are dissolved in 200 parts by volume of dry toluene in the presence of 262 parts of 4-hydroxy-N,Ndimethylbutyramide and 2 parts of aluminum isopropylate. The solution is heated for 8 hours, while collecting the toluene-ethanol azeotrope, in an apparatus provided with a distillation column at a controllable rate of reflux. After this it is filtered ,the solvent is evaporated in vacuo and the residue is distilled. An almost colorless, slightly yellow oil is obtained, the purity of which by chromatographic examination in the gaseous phase is of the order of 99.5%. Its boiling point is 175°C under 0.1 torr.48.5 parts of ethyl 4'-chlorophenoxyisobutyrate are dissolved in 200 parts by volume of dry toluene in the presence of 262 parts of 4-hydroxy-N,Ndimethylbutyramide and 2 parts of aluminum isopropylate. The solution is heated for 8 hours, while collecting the toluene-ethanol azeotrope, in an apparatus provided with a distillation column at a controllable rate of reflux. After this it is filtered ,the solvent is evaporated in vacuo and the residue is distilled. An almost colorless, slightly yellow oil is obtained, the purity of which by chromatographic examination in the gaseous phase is of the order of 99.5%. Its boiling point is 175°C under 0.1 torr.
The product can be recrystallized. For this, it is dissolved, for example, at the ambient temperature in petrol ether, ethyl ether or isopropyl ether, and this solution is cooled at about -50°C while stirring. After drying over sulfuric acid under vacuum, white needles of very great purity are thus obtained.
Therapeutic Function
Antihyperlipidemic클로피브라이드 준비 용품 및 원자재
원자재
준비 용품
클로피브라이드 공급 업체
글로벌( 9)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24017 | 58 |