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드모페부민

드모페부민 구조식 이미지

카스 번호:: 3735-45-3

한글명:: 드모페부민

동의어(한글):: 드모페부민

상품명:: Dmophebumine

동의어(영문):: Revatrine;Vetrabutine;Dmophebumine;N,N-Dimethyl-α-(3-phenylpropyl)veratrylamine;1-(3,4-Dimethoxyphenyl)-4-phenylbutyldimethylamine;Benzenebutanamine, α-(3,4-dimethoxyphenyl)-N,N-dimethyl-;1-(3,4-dimethoxyphenyl)-N,N-dimethyl-4-phenylbutan-1-amine;1-(3,4-dimethoxyphenyl)-N,N-dimethyl-4-phenyl-butan-1-amine

CBNumber:: CB11178558

분자식:: C20H27NO2

포뮬러 무게:: 313.438

MOL 파일:: 3735-45-3.mol

속성

안전

용도

공급 업체 3

드모페부민 속성

끓는 점: bp0.1 166-168°

밀도: 1.027±0.06 g/cm3(Predicted)

산도 계수 (pKa): 8.54±0.50(Predicted)

안전

드모페부민 C화학적 특성, 용도, 생산

Originator

Monzal ,Boenhringer Ingelheim

Manufacturing Process

1.5 mole magnesium and 1 mole 3-phenylpropyl bromide were used for preparing of ester solution of Grignar reagent. 1 mole (3,4- dimethoxyphenyl)dimethylaminoacetonitrile in absolute ester was added to above reagent dropwise. Then the mixture was heated for 3 hours to reflux. On cooling it was poured into ice with 12% hydrochloric acid. The ester layer was separated. The water layer was alkalized with concentrate ammonia and ammonium chloride. The precipitated oil was dissolved in ester, dried over sodium sulfate and distilled in vacuum after removing of ester to give α-(3,4- dimethoxyphenyl)-N,N-dimethylbenzenebutanamine (vertabutine); BP: 166°- 168°C/0.1 mm Hg. Yield 85%. The free base may be turn into colorless hydrochloride by adding of equivalent of hydrochloric acid in ester; MP: 146°- 148°C.

Therapeutic Function

Uterine relaxant

드모페부민 준비 용품 및 원자재

원자재

마그네슘 1-Bromo-3-phenylpropane

준비 용품

드모페부민 공급 업체

글로벌( 3)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30250	58

드모페부민 관련 검색:

Veratrylamine TOSLAB 807995 Dmophebumine