N-아세틸무라밀-알라닐-이소글루타미닐-알라닐-sn-글리세로-3-포스포에탄라민
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N-아세틸무라밀-알라닐-이소글루타미닐-알라닐-sn-글리세로-3-포스포에탄라민 속성
- 밀도
- 1.152
- 저장 조건
- -20°C
- 용해도
- 물: 용해성2mg/mL, 투명(따뜻한)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 1.39±0.50(Predicted)
- 색상
- 흰색에서 베이지색
- InChIKey
- ZVLWUMPAHCEZAW-HYGHKABSNA-N
- CAS 데이터베이스
- 83461-56-7
안전
WGK 독일 | 3 |
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N-아세틸무라밀-알라닐-이소글루타미닐-알라닐-sn-글리세로-3-포스포에탄라민 C화학적 특성, 용도, 생산
용도
Osteosarcoma.Mechanism of action
Being a phospholipid, mifamurtide accumulates in the lipid bilayer of the liposomes upon infusion. After application of the liposomal infusion, the drug is cleared from the plasma within minutes. However, it is concentrated in lung, liver, spleen, nasopharynx and thyroid, and the terminal half-life is 18 hours, which is longer than the natural substance.Clinical Use
Mifamurtide is an anticancer agent for the treatment of osteosarcoma, the most common primary malignancy of bone tissue mainly affecting children and adolescents. The drug was invented by Ciba-Geigy (now Novartis) in the early 1980s and the agent was subsequently licensed to Jenner Biotherapies in the 1990s. IDM Pharma bought the rights to the drug from Jenner in April 2003.In March 2009, mifamurtide was approved in the 27 European Union member states plus Iceland, Liechtenstein and Norway via a centralized marketing authorization. After the approval, IDM Pharma was acquired by Takeda, which began launching mifamurtide, as Mepact ®, in February 2010. Mifamurtide, a fully synthetic lipophilic derivative of muramyl dipeptide (MDP), is muramyl tripeptide phosphatidylethanolamine (MTP-PE), which is formulated as a liposomal infusion.N-아세틸무라밀-알라닐-이소글루타미닐-알라닐-sn-글리세로-3-포스포에탄라민 준비 용품 및 원자재
원자재
준비 용품
N-아세틸무라밀-알라닐-이소글루타미닐-알라닐-sn-글리세로-3-포스포에탄라민 공급 업체
글로벌( 65)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21662 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29899 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 23430 | 58 |
BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40067 | 58 |
N-아세틸무라밀-알라닐-이소글루타미닐-알라닐-sn-글리세로-3-포스포에탄라민 관련 검색:
트라 스투 주맙
Pazopanib
1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
Mitotan
RAT IL-2
PIERICIDIN A
Isopropyl-α-[2-methylhydrazino]-p-toluamide
Panitumumab
Teduglutide
Seractide
ecallantide
Docetaxel
Sofosbuvir
Posaconazole
Ibrutinib
N-Acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethano lamine