[(3R,7R)-7-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-methylbutan oate
|
|
[(3R,7R)-7-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-methylbutan oate 속성
- 녹는점
- 85°C
- 끓는 점
- 163-167 °C(Press: 2 Torr)
- 밀도
- 1.11±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 14.33±0.40(Predicted)
안전
[(3R,7R)-7-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-methylbutan oate C화학적 특성, 용도, 생산
개요
An alkaloid found in Duboisia myoporoides, the base crystallizes from EtOH in colourless, nacreous plates and has [α]20D - 9.0° (c 5.0, EtOH), or - 4.0° (c 5.0, H2O). It yields a crystalline hydrobromide as colourless needles, m.p. l70-2°C; [α]20D + 5.0° (c 20.0, H20); picrate, m.p. lS2-3°C; methiodide, m.p. 20S.SoC and the acetyl derivative, characterized as the hydrobromide, m.p. 197°C. The isovaleryl ester forms a hydrochloride, m.p. l24-SoC; [α]D + 2.6° (c 3.78, EtOH) and a hydrobromide, m.p. l76-7°C. Treatment of the hydrobromide with thionyl chloride gives norvaleroidine due to demethylation, a colourless syrup which furnishes a crystalline hydrobromide, m.p. 270°C; [α]20D + 1 ° (c 20.0, H20). On hydrolysis with aqueous Ba(OHh, the base gives dihydroxytropane and isovaleric acid while oxidation with KMn04 furnishes norvalieroidine and a base C13H190 4N, m.p. 136°C; [α]20D - 16.6° (c 7.4, EtOH).참고 문헌
Barger, Martin, Mitchell.,!. Chem. Soc., 1820 (1937)Barger, Martin, Mitchell., ibid, 1685 (1938)
Martin, Mitchell., ibid, 1155 (I 940)
Mitchell, Troutner., ibid, 1330 (I 947)
Fodor, Kovacs., ibid, 2341 (1953)
Fodor, Vincze, Toth., ibid, 1349 (1957)
Fodor, Vincze, Toth., ibid, 3219 (1961)
[(3R,7R)-7-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-methylbutan oate 준비 용품 및 원자재
원자재
준비 용품
[(3R,7R)-7-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-methylbutan oate 공급 업체
글로벌( 15)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 |
aileen@chemfaces.com | China | 7059 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Shanghai ChengShao Biological Technology Co., Ltd. | 021-61847300 13341622919 |
shcss01@163.com | China | 4809 | 58 |
| Zhejiang Lianshuo Biotechnology Co., Ltd. | 18616526224 |
lianshuo@vip.126.com | China | 9610 | 58 |
| Sichuan BioCrick Biotech Co., Ltd | 28-85433893 |
info@biocrick.com | CHINA | 4988 | 58 |
| Shanghai Fusheng Industrial Co., LTD | 021-52961053 13524666654 |
3004902811@qq.com | China | 9724 | 58 |