카프로맙펜데타이드

카프로맙펜데타이드
카프로맙펜데타이드 구조식 이미지
카스 번호:
145464-28-4
한글명:
카프로맙펜데타이드
동의어(한글):
카프로맙펜데타이드
상품명:
Capromab Pendetide
동의어(영문):
Prostascint;Cytogen 356;Capromab Pendetide;Oncoscint prostate;Research Grade Capromab (DHG01303);Immunoglobulin G 1 (mouse monoclonal 7E11-C5.3 anti-human prostatic carcinoma cell), disulfide with mouse monoclonal 7E11-C5.3 light chain, dimer, N(sup 6)-(N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)ethyl)-N-(carboxymethyl)glycyl)-N(sup 2)-(N-glycyl-L-tyrosyl)-L-lysine conjugate
CBNumber:
CB11379720
분자식:
C10H15N5O11P2
포뮬러 무게:
443.200522
MOL 파일:
145464-28-4.mol

카프로맙펜데타이드 속성

안전

카프로맙펜데타이드 C화학적 특성, 용도, 생산

용도

Monoclonal antibody.

일반 설명

Capromab (ProstaScint Kit for the preparation of In-111capromab pendetide, murine) is an MAb (murine IgG1 κ)that derives from an initial sensitization with a glycoproteinexpressed by prostate epithelium known as prostate surfacemembrane antigen (PSMA). The MAb recognizes PSMAspecifically and thus is specific for prostate adenocarcinomas.The drug is used in newly diagnosed patients withproven prostate cancer who are at high risk for pelvic lymphmetastasis. PSMA has been found in many primary andmetastatic prostate cancer lesions. The cytoplasmic domainmarker 7E11-C5.3 reacts with more than 95% of adenocarcinomasevaluated.
To join the indium-111 to the antibody, a linker-chelatoris used. This moiety is glycyltyrosyl-(N-ethylenetriaminepentaaceticacid)-lysine HCl.

카프로맙펜데타이드 준비 용품 및 원자재

원자재

준비 용품


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