ChemicalBook >제품 카탈로그 >Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1 구조식 이미지
카스 번호:
상품명:
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1
동의어(영문):
Anti-HMGB1 (HMG1) (N-terminal) antibody produced in rabbit;Anti-HMGB1 (HMG1) (C-terminal) antibody produced in rabbit;Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1 속성
저장 조건
-20°C
물리적 상태
buffered aqueous solution
생물학적 소스
rabbit
안전
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1 C화학적 특성, 용도, 생산
용도
Anti-HMGB1 (HMG1) (C-terminal) antibody produced in rabbit has been used in ELISA and immunofluorescence.
일반 설명
The High Mobility Group (HMG1) is secreted by activated monocytes and macrophages. The gene is mapped to human chromosome 13q12.
Biochem/physiol Actions
In the nucleus, HMGB1 (high-mobility group protein B1) works as a nucleosome stabilizer and transcriptional regulator. It also exhibits chaperone-like activity and suppresses aggregation of polyglutamine. It has a role in inflammation and autophagy. HMGB1 can interact with toll-like receptor (TLR) 2 and 4, interleukin-1β, chemokine (C-X-C motif) ligand 12 (CXCL12) and pathogen-associated molecular pattern (PAMP) molecules. It also works as a damage-associated molecular pattern molecule (DAMP).
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1 준비 용품 및 원자재
원자재
준비 용품
Anti-Amphoterin, Anti-High mobility group box 1, Anti-High mobility group protein 1 공급 업체
