ChemicalBook >제품 카탈로그 >(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine 구조식 이미지

카스 번호:: 327623-37-0

상품명:: (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

동의어(영문):: Aprepitant Impurity 1;Aprepitant Impurity 11;Fosaprepitant Impurity 30;Aprepitant M2 Metabolite Enantiomer;Aprepitant Impurity 1 Hydrochloride;Aprepitant Impurity 10 Hydrochloride;Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer;Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1’Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant;(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

CBNumber:: CB12657010

분자식:: C20H18F7NO2

포뮬러 무게:: 437.35

MOL 파일:: 327623-37-0.mol

속성

안전

용도

공급 업체 40

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine 속성

끓는 점: 387.9±42.0 °C(Predicted)

밀도: 1.37±0.1 g/cm3(Predicted)

산도 계수 (pKa): 6.93±0.60(Predicted)

안전

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine C화학적 특성, 용도, 생산

용도

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine 준비 용품 및 원자재

원자재

준비 용품

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine 공급 업체

글로벌( 40)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14335	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	5056	50
CEG Chemical Science&Technology Co., Ltd.	Mobile:13665161512		China	1785	58
GIHI CHEMICALS CO.,LTD	0086-571-86217390	Sales@gihichem.com	China	861	58
Shanghai Ranxon Chemical Co., Ltd.	13148101715	2073632910@qq.com	China	38	55
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9798	50

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine 관련 검색:

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine Aprepitant Fosaprepitant dimeglumine Aprepitant Aprepitant Aprepitant Fosaprepitant Impurity 6 (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Aprepitant Fosaprepitant Impurity 5 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one 1,1,1-Trimethoxy-2-chloroethane Aprepitant Benzyl dihydrogen phosphate