4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl

4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl C화학적 특성, 용도, 생산

제조 방법

The preparation of 4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl is as follows:10.0 g (29.0 mmol) of 5-[4-chloro-2,6-difluorophenyl)difluoromethoxy]-1,2,3-trifluorobenzene and 8.47 g (29.6 mmol, 1.02 equivalent amount) of 4'-pentyl-3-fluoro-4-biphenylboronic acid were placed in a 300-ml SUS autoclave, after which 467 mg (0.05 equivalent amount) of TBAB, 16.6 mg (0.0012 equivalent amount) of 2-dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl (purchased from Johnson Matthey Japan Inc.), and 49.4 mg (0.0004 equivalent amount) of 5% palladium carbon were placed in the autoclave. The autoclave was subsequently sealed, and the atmosphere therein was replaced with nitrogen. Thereafter, 30 ml of deaerated water and 10 ml of deaerated DMAc was added thereto, and 4.5 g (1.5 equivalent amount) of triethylamine was further added thereto, followed by stirring at the reaction liquid temperature of 99°C for 4 hours. The mixture was stirred at room temperature for 20 minutes, and 50 ml of toluene and 30 ml of water were added to the reaction mixture, followed by additional stirring for 15 minutes. The reaction yield was 97.7% (quantified by 19F NMR). The organic layer was subjected to suction filtration (using Celite), the filtrate was concentrated, and then the residue was purified using column chromatography. The crude substance thus obtained was recrystallized with a mixed solvent of denatured ethanol and heptane, thereby obtaining 4-[difluoro-(3,4,5-trifluoro-phenoxy)-methyl]-2',3,5-trifluoro-4"-pentyl-[1,1';4',1"]terphenyl in the form of a white solid. Amount obtained: 14.8 g (isolation yield 93.0%, purity 99.9%). 

4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl 준비 용품 및 원자재

원자재

준비 용품

4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	16209	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29826	58
Univar Solutions(China) Co., Ltd.	+8615902132654	ivy.zhuang@univarsolutions.com	China	654	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	13095	58
Shaoxin Catsyn Co., Ltd.	+undefined-0575-82040869 +86-0575-82040869;	sales@catsyn.com	China	6116	58
Wulechem Co., Ltd.	13761914825	wulesian@wulechem.com	China	306	58
Shijiazhuang Yesheng Chemical Technology Co., Ltd	0311-68030586 18031147013	yeshengchemical@163.com	China	2875	58
Beijing Bayishikong LCD Technology Co., Ltd.	0086-18600516188 18600516188	zhangshupo@aliyun.com	China	303	58
Hunan chemfish Scientific co.,ltd	0731-85567275 18974947952	sales@chemfish.com	China	4898	58

4-[Difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl 관련 검색: