둘라글루타이드
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둘라글루타이드 속성
안전
유해 물질 데이터 | 923950-08-7(Hazardous Substances Data) |
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둘라글루타이드 C화학적 특성, 용도, 생산
개요
Dulaglutide, a GLP-1 receptor agonist that is administered subcutaneously once weekly, has been approved since 2014 for the treatment of adults with type 2 diabetes.상표명
Dulaglutide is marketed by Eli Lilly as Trulicity.Mechanism of action
The dulaglutide mechanism of action involves activation of the GLP-1 receptor, a membrane-bound cell-surface receptor coupled to adenylyl cyclase in b cells. Thus, it increases intracellular cyclic AMP in these cells, leading to a glucose-dependent release of insulin. Dulaglutide also reduces secretion of glucagon and slows gastric emptying.Mode of action
The mechanism of action of dulaglutide is as a Glucagon-like Peptide-1 (GLP-1) Agonist. Structurally, dulaglutide is made by replacing Ala with Gly at position 8, Glu with Gly at position 22, and Arg with Gly at position 36 on the GLP-1 (7-37) chain, with an average biological half-life of up to 90h.둘라글루타이드 준비 용품 및 원자재
원자재
준비 용품
둘라글루타이드 공급 업체
글로벌( 134)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 1142 | 58 |
Shanghai Minbiotech Co., Ltd. | +8617315815539 |
sales@minbiotech.com | CHINA | 129 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 |
kyra@quanjinci.com | China | 1534 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 |
anna@api-made.com | China | 2944 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 |
asdf@shanghaihg.cn | China | 265 | 58 |
Wuhan Cell Pharmaceutical Co., Ltd | +86-13129979210 +86-13129979210 |
sales@cellwh.com | China | 376 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10978 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 |
info@hyper-chem.com | China | 209 | 58 |