TOMATINE
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TOMATINE 속성
- 녹는점
- 300-305°C
- 알파
- D20 -18° (c = 0.55 in pyridine)
- 끓는 점
- 806.69°C (rough estimate)
- 밀도
- 1.48±0.1 g/cm3 (20 ºC 760 Torr)
- 굴절률
- 1.5280 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨, 가열), 피리딘(약간 용해됨)
- 산도 계수 (pKa)
- 12.77±0.70(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- Merck
- 14,9545
- LogP
- 2.220 (est)
- CAS 데이터베이스
- 17406-45-0
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 23/25-22 | ||
| 안전지침서 | 45-24/25-22 | ||
| 유엔번호(UN No.) | 1544 | ||
| RTECS 번호 | XW1050000 | ||
| HS 번호 | 29329990 | ||
| 유해 물질 데이터 | 17406-45-0(Hazardous Substances Data) | ||
| 독성 | LD orally in rats: 900-1000 mg/kg (Wilson) |
TOMATINE C화학적 특성, 용도, 생산
개요
This glycosidic alkaloid has been obtained from the dried leaves of Lycopersicum pimpinelli/olium (Syn. Solanum racemigerum) and also occurs in L. esculentum; L. hirsutum; L. peruvianum; L. peruvianum var. chutatum and L. putatum. The alkaloid forms colourless needles from MeOH and has a somewhat indefinite melting point about 270°C. It is laevorotatory with [α]20D - 30° (pyridine) and on hydrolysis with H2S04 yields tomatidine, I mole of galactose, 2 moles of glucose and 1 mole of xylose. The tetrasaccharide unit is known as lycotetraose. Partial hydrolysis with acid yields a series of products depending upon which, and how many, of the sugar residues are split off from the molecule. Those which have been isolated are: tomatidine lycotriose I (galactose-glucose-glucose); tomatidine lycotriose II (galactose-glucose-xylose); tomatidine lycobiose (galactose-glucose) and tomatidine-galactose.화학적 성질
Faintly beige powder용도
Tomatine is used as an antiproliferatice agent used in the suppression of breast adenocarcinoma cells.정의
ChEBI: A steroid alkaloid that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galac ose.Purification Methods
Tomatine is recrystallised from MeOH, EtOH, aqueous EtOH or dioxane/NH3. It is almost insoluble in pet ether, Et2O or H2O. [Reichstein Angew Chem 74 887 1962, Beilstein 27 III/IV 1954.]참고 문헌
Fontaine et al., Arch. Biochem., 18,467 (1948)Kuhn, Low., Ber., 81, 552 (1948)
Kuhn, Low, Gauhe., ibid, 83,448 (1950)
Fontaine et al., Arch. Biochem., 27,461 (1950)
Fontaine et al., J. Amer. Chern. Soc., 73, 878 (1951)
Kuhn, Low, Trischmann., Angew. Chern., 68, 212 (1956)
Kuhn et al., Ber., 90, 203 (1957)
TOMATINE 준비 용품 및 원자재
원자재
준비 용품
TOMATINE 공급 업체
글로벌( 163)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 |
jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12468 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 3001 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8829 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
TOMATINE 관련 검색:
트라이에틸렌 글라이콜 2,6,8-트리메틸노난올-4 디프로필렌 글리콜 부톡시 에테르 2-부톡시-1-프로판올
2-heptyltetrahydrofuran
2-(OCTADECYLOXY)ETHANOL
12-AMINO-1-DODECANOL
Dulcitol
1,12-OCTADECANEDIOL
TOMATINE
Dihydrocholesterol
PHYTANE
5α-Cholestane
2-(DODECYLOXY)ETHANOL
TOMATIDINE
3-O-HEXADECYL-SN-GLYCEROL
1-BUTOXYETHOXY-2-PROPANOL
3-BUTOXY-PROPIONALDEHYDE DIETHYL ACETAL