FAUC-365

FAUC-365 구조식 이미지
카스 번호:
474432-66-1
상품명:
FAUC-365
동의어(영문):
FAUC-365;3-dichloro-;FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2;Benzo[b]thiophene-2-carboxamide, N-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-;FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide;inhibit,Parkinson's disease,Dopamine Receptor,D3 receptor,FAUC365,Dopamine,Inhibitor,FAUC-365,schizophrenia,SPET,Radioligand,FAUC 365
CBNumber:
CB13067544
분자식:
C23H25Cl2N3OS
포뮬러 무게:
462.4351
MOL 파일:
474432-66-1.mol

FAUC-365 속성

끓는 점
680.3±55.0 °C(Predicted)
밀도
1.300±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
insoluble in EtOH; insoluble in H2O; ≥5.79 mg/mL in DMSO
물리적 상태
결정성 고체
산도 계수 (pKa)
14.55±0.46(Predicted)
색상
Off-white to light yellow

안전

FAUC-365 C화학적 특성, 용도, 생산

개요

FAUC-365 is a dopamine D3 receptor antagonist (Ki = 0.5 nM). It is selective for dopamine D3 receptors over dopamine D1, D2L, D2S, and D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 μM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT2 (Kis = 0.36 and 2 μM, respectively). FAUC-365 (1-10 mg/kg) prevents memory impairment in the novel object recognition test in dopamine transporter knockdown (DAT-KD) mice when administered prior to object learning.

FAUC-365 준비 용품 및 원자재

원자재

준비 용품


FAUC-365 공급 업체

글로벌( 29)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ATK CHEMICAL COMPANY LIMITED
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TargetMol Chemicals Inc.
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InvivoChem
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Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
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Amadis Chemical Company Limited
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sales@amadischem.com China 131980 58
BOC Sciences 16314854226
info@bocsci.com United States 9926 65
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921
sales@pharmacodia.com China 2317 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9707 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
2853530910@QQ.com China 8017 62
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
info@SuperLan-chem.com China 9941 58

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