1,1,3,3-Tetramethylurea
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1,1,3,3-Tetramethylurea 속성
- 녹는점
- −1 °C(lit.)
- 끓는 점
- 177 °C(lit.)
- 밀도
- 0.968 g/mL at 20 °C(lit.)
- 굴절률
- n
20/D 1.451(lit.)
- 인화점
- 150 °F
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 물, 석유 에테르 및 일반 용매와 섞일 수 있습니다.
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 2.0(at 25℃)
- 색상
- 무색~담황색 투명
- 수소이온지수(pH)
- 5-8 (25℃, 1M in H2O)
- 상대극성
- 5
- 냄새
- 희미한 기분 좋은 냄새
- 수용성
- H2O: 20°C에서 1M, 혼화성
- Merck
- 14,9230
- BRN
- 773898
- Dielectric constant
- 24.460000000000001
- InChIKey
- AVQQQNCBBIEMEU-UHFFFAOYSA-N
- CAS 데이터베이스
- 632-22-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,T | ||
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위험 카페고리 넘버 | 22-61 | ||
안전지침서 | 53-45 | ||
유엔번호(UN No.) | NA 1993 / PGIII | ||
WGK 독일 | 3 | ||
RTECS 번호 | YU2625000 | ||
F 고인화성물질 | 3-10 | ||
TSCA | Yes | ||
HS 번호 | 29241900 | ||
유해 물질 데이터 | 632-22-4(Hazardous Substances Data) | ||
독성 | LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen) | ||
기존화학 물질 | 2015-3-6530 |
1,1,3,3-Tetramethylurea C화학적 특성, 용도, 생산
화학적 성질
Tetramethylurea is a clear colorless to pale yellow liquid with mild aromatic odor that is miscible with water and many organic solvents. Unusual for an urea is the liquid state of tetramethylurea in a range of > 170 °C.용도
Tetramethylurea is used as a solvent in dyestuff industries, in condensation reaction and intermediates in surfactant. It is utilized for base catalyzed isomerization and alkylation hydrocyanation due to its low permittivity. It reacts with oxalyl chloride to prepare tetramethyl chloroformamidinium chloride, which is used for the conversion of carboxylic acids and dialkyl phosphates to anhydrides and pyrophosphates respectively.정의
ChEBI: 1,1,3,3-tetramethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1, 1, 3 and 3 respectively. Metabolite observed in cancer metabolism. It has a role as a human metabolite.제조 방법
The reaction of dimethylamine with phosgene in the presence of e. g. 50 % sodium hydroxide solution and subsequent extraction with 1,2-dichloroethane yields tetramethylurea in 95% yield.Safety Profile
Moderately toxic by ingestion and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. Combustible when exposed to heat, flame, and oxidizers. To fight fire, use foam, mist, spray, dry chemicals. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Dry it over BaO and distil it under nitrogen. It denatures proteins in H2O. [Elbaum & Herskovits Biochemistry 13 1268 1974, Kane Anal Biochem 53 350 1973, Beilstein 4 IV 225.]1,1,3,3-Tetramethylurea 준비 용품 및 원자재
원자재
준비 용품
1,1,3,3-Tetramethylurea 공급 업체
글로벌( 367)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10312 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7621 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
1,1,3,3-Tetramethylurea 관련 검색:
모노메틸유레아 트리스(2,3-디브로모프로필) 아이소시안요산염 1,3,5-트리스(2-하이드록시에틸)이소시아누레이트 1,3-디메틸-2-이미다졸리디논 아미노필린 디프로필린 트리알릴 이소시아누르산염 3-이소부틸-1-메틸삭틴
4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
PIPERAZINE DIHYDROCHLORIDE
3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
1-Hydroxybenzotriazole
Olaparib Impurity 14
5-Bromo-2-fluorobenzonitrile
Cyclopropanecarbonyl Chloride
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzonitrile
2-Propanone, 1-[4,5-dihydro-2-(4-methyl-1-piperazinyl)-4-thioxo-3H-1,5-benzodiazepin-3-ylidene]-
Olaparib Impurity 31