GELATINASE A

GELATINASE A 구조식 이미지
카스 번호:
193807-58-8
상품명:
GELATINASE A
동의어(영문):
MMPL;MMP-2;MMP-1;EC 3.4.24.7;EC 3.4.24.3;MMP-2, HUMAN;EC 3.4.24.24;EC: 3.4.24.3;GELATINASE A;COLLAGENASE D
CBNumber:
CB1309850
분자식:
C21H19NO4S
포뮬러 무게:
381.44
MOL 파일:
193807-58-8.mol
MSDS 파일:
SDS

GELATINASE A 속성

녹는점
146-147 °C
끓는 점
595.9±60.0 °C(Predicted)
밀도
1.297±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
≤25mM in DMSO
산도 계수 (pKa)
3.26±0.10(Predicted)
물리적 상태
가루
색상
연한 갈색
CAS 데이터베이스
193807-58-8

안전

위험품 표기 B,Xi
위험 카페고리 넘버 36/37/38-42
안전지침서 23-26-36-24/25
WGK 독일 2
F 고인화성물질 10-21

GELATINASE A C화학적 특성, 용도, 생산

용도

Matrix metalloproteinase-2 (MMP2) human has been used:
  • As a standard in zymography to measure gelatinolytic activity of MMP2.
  • In enzymatic method for dissociation of brain tissue to single cells.

일반 설명

Matrix metalloproteinase-2 (MMP-2) also known as gelatinase or type IV collagenase is a 72kDa protein. MMP-2 is a member of matrix metalloproteinase (MMP) family of enzymes. Basic structure of MMP2 contains signal peptide domain that targets the enzyme for secretion, the pro-peptide domain, which is removed when the enzyme is activated and the catalytic site containing gelatin-binding domain.

Biochem/physiol Actions

Matrix Metalloproteinase-2 (MMP-2) cleaves gelatin, type IV, V, VII, X, and XI collagens, fibronectin, elastin, laminin, proteoglycans and a range of non extracellular matrix (ECM ) components. MMP-2 cleaves native type I collagen to N-terminal ? and C-terminal ? fragments identical to those generated by interstitial collagenases. MMP2 and MMP9 play an essential role in matrix degradation and they are implicated in the maintenance of neovascularization. In mice, deletion or inhibition of MMP2 protects against myocardial rupture.

GELATINASE A 준비 용품 및 원자재

원자재

준비 용품


GELATINASE A 공급 업체

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