4-하이드록시티오벤자미드
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4-하이드록시티오벤자미드 속성
- 녹는점
- 181-185℃
- 끓는 점
- 320.4±44.0 °C(Predicted)
- 밀도
- 1.338±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 9.24±0.26(Predicted)
- 색상
- 연노랑
- InChI
- InChI=1S/C7H7NOS/c8-7(10)5-1-3-6(9)4-2-5/h1-4,9H,(H2,8,10)
- InChIKey
- VDTNKXSVUGXUOJ-UHFFFAOYSA-N
- SMILES
- C1(C(N)=S)=CC=C(O)C=C1
- CAS 데이터베이스
- 25984-63-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21/22-36/37/38-43-22 | ||
안전지침서 | 26-36/37/39-36/37 | ||
HS 번호 | 29242990 |
4-하이드록시티오벤자미드 C화학적 특성, 용도, 생산
화학적 성질
4-Hydroxythiobenzamide has an appearance ranging from light orange to yellow to green, powder to crystalline, melting point 192 °C, soluble in methanol.용도
4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.Synthesis
4-Hydroxythiobenzamide is an important intermediate of Febuxostat, a new anti-gout drug. A patent discloses a method for preparing p-hydroxythiobenzamide. Specifically, a certain amount of water, p-cyanophenol, sodium hydrosulfide, and secondary amine are mixed evenly. At a specific temperature, an organic weak acid is added dropwise. After the reaction is completed, the mixture is filtered, and the filter cake is dried to obtain 4-Hydroxythiobenzamide.![4-HYDROXYTHIOBENZAMIDE 4-HYDROXYTHIOBENZAMIDE](/NewsImg/2024-05-29/6385257370111178608824099.png)
4-하이드록시티오벤자미드 준비 용품 및 원자재
원자재
준비 용품
4-하이드록시티오벤자미드 공급 업체
글로벌( 538)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Jinan Jianfeng Chemical Co., Ltd | +8615562555968 |
info@pharmachemm.com | China | 243 | 58 |
JUYE XIANDAI fine chemistry Co.,Ltd | +86-18958038633; +8618958038633 |
tony@sdhypharma.com | China | 64 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3415 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10977 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
4-하이드록시티오벤자미드 관련 검색:
티오벤즈아미드 벤즈아마이드
ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
Febuxostat
4-HYDROXYTHIOBENZAMIDE
4-METHOXYTHIOBENZAMIDE
2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBOTHIOAMIDE
6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-THIONE
Tritiozine
Vanitiolide
4-Ethoxybenzenecarbothioamide
4-[5-(TRIFLUOROMETHYL)PYRID-2-YLOXY]THIOBENZAMIDE
4-METHOXY-3-NITROBENZENE-1-CARBOTHIOAMIDE
2,3-DIHYDROBENZO[B]FURAN-5-CARBOTHIOAMIDE
1,3-BENZODIOXOLE-5-CARBOTHIOAMIDE
1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID