5-Methylcytidine

5-Methylcytidine 구조식 이미지
카스 번호:
2140-61-6
상품명:
5-Methylcytidine
동의어(영문):
4-aMino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidin-2(1H)-one;5-Me-Cr;NSC 363933;5-METHYLCYTIDINE;5-Methyicytidine;5-Methylcytidine>Cytidine, 5-Methyl-;Cytarabine EP Impurity G;5-METHYLCYTIDINE USP/EP/BP;5-METHYLCYTIDINE, 98.0+%(LC)(T)
CBNumber:
CB1352003
분자식:
C10H15N3O5
포뮬러 무게:
257.24
MOL 파일:
2140-61-6.mol
MSDS 파일:
SDS

5-Methylcytidine 속성

녹는점
212-215 °C (dec.) (lit.)
끓는 점
537.5±60.0 °C(Predicted)
밀도
1.79
굴절률
15 ° (C=2, H2O)
저장 조건
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(소량으로 용해)
산도 계수 (pKa)
pK1:4.21 (25°C)
물리적 상태
고체
물리적 상태
단단한 모양
색상
미색부터 페일 베이지까지
수소이온지수(pH)
4.3
수용성
water: 25mg/mL, clear, colorless
최대 파장(λmax)
287 (pH 0);277 (pH 7)
안정성
흡습성
InChI
InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1
InChIKey
ZAYHVCMSTBRABG-JXOAFFINSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(C)C(N)=NC2=O)[C@H](O)[C@@H]1O
CAS 데이터베이스
2140-61-6(CAS DataBase Reference)

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36-24/25
WGK 독일 3
HS 번호 29389090

5-Methylcytidine C화학적 특성, 용도, 생산

개요

The methylation of carbon 5 in cytidine (m5C, 5-methylcytidine) has been identified as a widespread epitranscriptomic mark. 5-Methylcytidine is mostly found in tRNA and rRNA. 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA and DNA for certain organisms. Roughly one to two residues of 5-methylcytidine occur in every 1,000 RNA residues. It has been used in epigenetics research, especially in studies involving DNA methylation processes involved in the establishment of genomic imprinting and the control of gene expression and differentiation.

화학적 성질

White powder

용도

5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.

일반 설명

5-Methylcytidine is a component of RNA in Escherichia coli. It is present in the RNA of plant, animal and bacterial origin. It is one of the C derivative present in transfer RNA (tRNA).

5-Methylcytidine 준비 용품 및 원자재

원자재

준비 용품


5-Methylcytidine 공급 업체

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