Benzyl vinylcarbamate
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Benzyl vinylcarbamate 속성
- 녹는점
- 43-44°C
- 끓는 점
- 272℃
- 밀도
- 1.089
- 인화점
- 118℃
- 저장 조건
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 11.04±0.46(Predicted)
- 색상
- 흰색에서 황백색까지
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험 카페고리 넘버 | 36/37/38 | ||
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안전지침서 | 26-36/37/39 |
그림문자(GHS): | |||||||||||||||
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신호 어: | Warning | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Benzyl vinylcarbamate C화학적 특성, 용도, 생산
제조 방법
A 1-L flask was equipped with a variable speed pump, a mechanical stirrer, a temperature controller, a 4" (10 cm) column packed with ceramic saddles, a distillation head, a spiral condenser (cooled with water at 10–15 ℃), and a receiver. The flask was charged with toluene (150–200 mL) and phenothiazine (0.5 g) and the solution was heated to 105–110 ℃. The receiver was charged with benzyl alcohol (86 g, 0.8 mol), phenothiazine (0.05 g), and triethylamine (0.1–0.3 g). This mixture was cooled in ice and stirred. A solution of acryloyl azide (1 mol), prepared as described above, was pumped into the distillation flask over a period of 4–5 h, maintaining the pot temperature at 105–110 ℃ with a heating mantle. The vapor temperature varied, depending on the rate of addition of the azide, but was in the range 80–100 ℃. The distillate was passed directly into the benzyl alcohol mixture. After the addition of acryloyl azide, the distillation continued, generating a further 10–20 mL of toluene. The receiver was then removed from the distillation set-up, and its contents were stirred at 0–5 ℃ for 1– 2 h. The product mixture was then allowed to gradually warm to room temperature and was stirred until HPLC analysis indicated complete reaction. The mixture was then concentrated in vacuo to a weight of 200–250 g. The residue was treated with heptane (300–350 mL) and cooled to 15 ℃ with stirring. A few seed crystals of benzyl N-vinyl carbamate 810 were added, and the mixture was stirred for 2–3 h. The product was collected by filtration, washed with heptane, and dried in vacuo. Yield 115–128 g (65–72%); mp 41–44 ℃.주요 응용
Benzyl-N-vinyl carbamate (Z-vinylamine; Benzyl vinylcarbamate) is a valuable synthetic intermediate. This compound undergoes alkylation readily on the carbon R to the nitrogen, a property that has been used in the synthesis of a-lactam antibiotics. Z-vinylamine can be readily polymerized into polyvinyl amine derivatives[1].Synthesis Reference(s)
The Journal of Organic Chemistry, 54, p. 4649, 1989 DOI: 10.1021/jo00280a036Benzyl vinylcarbamate 준비 용품 및 원자재
원자재
준비 용품
Benzyl vinylcarbamate 공급 업체
글로벌( 64)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21149 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30250 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 |
sales@tnjchem.com | China | 25363 | 58 |
JUYE XIANDAI fine chemistry Co.,Ltd | +86-18958038633; +8618958038633 |
tony@sdhypharma.com | China | 64 | 58 |
Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 |
CB@aromsyn.com | China | 19185 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Benzyl vinylcarbamate 관련 검색:
Z-DEHYDRO-ALA-OME
Z-DEHYDRO-ALA-OH
BENZYL N-STYRYLCARBAMATE
2,3,4,5,6-PENTAMETHYLBENZYL N-(1,2,2-TRICHLOROVINYL)CARBAMATE
3-CHLOROBENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
4-(TRIFLUOROMETHYL)BENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
4-ISOPROPYLBENZYL N-(1,2,2-TRICHLOROVINYL)CARBAMATE
4-CHLOROBENZYL N-STYRYLCARBAMATE
2,6-DICHLOROBENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
2,6-DICHLOROBENZYL N-STYRYLCARBAMATE
2,4-DICHLOROBENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
4-(TERT-BUTYL)BENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
4-BROMOBENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
4-METHOXYBENZYL N-STYRYLCARBAMATE
4-METHOXYBENZYL N-[2-(2-FURYL)VINYL]CARBAMATE
4-CHLORO-3-NITROBENZYL N-(1,2,2-TRICHLOROVINYL)CARBAMATE
4-METHOXYBENZYL N-(4-CHLOROSTYRYL)CARBAMATE
4-CHLOROBENZYL N-[2-(2-FURYL)VINYL]CARBAMATE