(S,R,S)-AHPC-PEG6-Azide
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(S,R,S)-AHPC-PEG6-Azide 속성
- 저장 조건
- 2-8°C
안전
(S,R,S)-AHPC-PEG6-Azide C화학적 특성, 용도, 생산
용도
Protein degrader builiding block (S,R,S)-AHPC-PEG6-Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a von Hippel–Lindau (VHL)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with an alkyne on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.(S,R,S)-AHPC-PEG6-Azide 준비 용품 및 원자재
원자재
준비 용품
(S,R,S)-AHPC-PEG6-Azide 공급 업체
글로벌( 11)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2996 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9941 | 58 |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 |
1924344760@qq.com | China | 4824 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 |
1927928688@qq.com | China | 1382 | 58 |
Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 |
malulu@leyan.com | China | 54986 | 58 |
Zhengzhou convergence chemical co., LTD | 0371-0371-55153829 18003835034 |
2853979819@qq.com | China | 9426 | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 |
czbjpharma@126.com | China | 18488 | 58 |
Wuhan Yuxiang Medical Technology Co., Ltd. | 13971275651 |
sales@whyxpharma.com | China | 4351 | 58 |