2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- 구조식 이미지
카스 번호:
2244881-69-2
상품명:
2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-
동의어(영문):
STING-IN-3;C-171 STING inhibitor;N-(4-hexylphenyl)-5-nitrofuran-2-carboxamide;2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro-;genes,inhibit,ERIS,TMEM173,mmSTING,Inhibitor,Stimulator of Interferon Genes,STING,MPYS,MITA,stimulator,hsSTING,STINGIN3,interferon,STING IN 3
2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- C화학적 특성, 용도, 생산
개요
C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM.
2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- 준비 용품 및 원자재
원자재
준비 용품
2-Furancarboxamide, N-(4-hexylphenyl)-5-nitro- 공급 업체