펜클로페낙

펜클로페낙
펜클로페낙 구조식 이미지
카스 번호:
34645-84-6
한글명:
펜클로페낙
동의어(한글):
펜클로페낙
상품명:
fenclofenac
동의어(영문):
Flenac;R 67408;RX 67408;fenclofenac;[o-(2,4-Dichlorophenoxy)phenyl]acetic acid;Benzeneacetic acid, 2-(2,4-dichlorophenoxy)-;2-[2-(2,4-dichlorophenoxy)phenyl]acetic acid
CBNumber:
CB1885619
분자식:
C14H10Cl2O3
포뮬러 무게:
297.136
MOL 파일:
34645-84-6.mol

펜클로페낙 속성

녹는점
135.0℃
끓는 점
410.72°C (rough estimate)
밀도
1.3076 (rough estimate)
굴절률
1.5209 (estimate)
저장 조건
Hygroscopic, -20°C Freezer, Under inert atmosphere
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
pKa 4.53 (Uncertain)
색상
황백색부터 연한 갈색까지
수용성
8.439mg/L(25 ºC)
안정성
흡습성

안전

독성 LD50 oral in rat: 2280mg/kg

펜클로페낙 C화학적 특성, 용도, 생산

용도

Anti-inflammatory.

World Health Organization (WHO)

Fenclofenac, a nonsteroidal anti-inflammatory agent, was introduced in 1978 for the treatment of rheumatic disorders. By 1984 its use in the United Kingdom was associated with serious adverse effects, predominantly skin rashes, some of which were fatal. This led to the UK Committee on Safety of Medicine's refusal to renew the product licence and to the subsequent withdrawal of the drug by the manufacturer in all countries in which it was marketed.

펜클로페낙 준비 용품 및 원자재

원자재

준비 용품


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