Deslorelin아세테이트

Deslorelin아세테이트 C화학적 특성, 용도, 생산

개요

Deslorelin Acetate is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production.

용도

Deslorelin acetate is an injectable gonadotropin-releasing hormone (GnRH) super-agonist (also known as an LHRH agonist), used in treatment of precocious puberty and commonly used in veterinary medicine to induce ovulation in mares.

제조 방법

Deslorelin acetate is synthesized from the corresponding protected amino acid monomers by solid or liquid phase synthesis.

참고 문헌

[1] C L ACKERMANN. Ovarian activity reversibility after the use of deslorelin acetate as a short-term contraceptive in domestic queens.[J]. Theriogenology, 2012, 78 4: 817-822. DOI:10.1016/j.theriogenology.2012.03.030.
[2] R. NOVOTNY . Reversible suppression of sexual activity in tomcats with deslorelin implant[J]. Theriogenology, 2012, 78 4: Pages 848-857. DOI:10.1016/j.theriogenology.2012.03.035.
[3] Y CETIN. Long-term effect of deslorelin implant on ovarian pre-antral follicles and uterine histology in female rats.[J]. Reproduction in Domestic Animals, 2013, 48 2: 195-199. DOI:10.1111/j.1439-0531.2012.02128.x.
[4] BR?NDLI SP. Long-term effect of repeated deslorelin acetate treatment in bitches for reproduction control.[J]. Theriogenology, 2021: 73-82. DOI:10.1016/j.theriogenology.2021.07.015.

Deslorelin아세테이트 준비 용품 및 원자재

원자재

준비 용품

Deslorelin아세테이트 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177; +8617531190177	peter@yan-xi.com	China	6011	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9626	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58

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