ambuic acid

ambuic acid 구조식 이미지
카스 번호:
340774-69-8
상품명:
ambuic acid
동의어(영문):
ambuic acid;(2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid;2-Butenoic acid, 4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-, (2E)-
CBNumber:
CB21380277
분자식:
C19H26O6
포뮬러 무게:
350.41
MOL 파일:
340774-69-8.mol

ambuic acid 속성

저장 조건
Store at -20°C
용해도
DMSO: soluble; Ethanol: soluble; Methanol: soluble
물리적 상태
고체
색상
회백색

안전

ambuic acid C화학적 특성, 용도, 생산

개요

Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi, including F. solani, H. sativum, and C. gramineum, but not P. oryzae, R. solani, or B. cinerea. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 μg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.

ambuic acid 준비 용품 및 원자재

원자재

준비 용품


ambuic acid 공급 업체

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