(S)-(+)-3-하이드록시 사하이드로 퓨란
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(S)-(+)-3-하이드록시 사하이드로 퓨란 속성
- 알파
- 18.5 º (c=2 MeOH)
- 끓는 점
- 80 °C/15 mmHg (lit.)
- 밀도
- 1.103 g/mL at 25 °C (lit.)
- 증기압
- 47Pa at 25℃
- 굴절률
- n
20/D 1.45(lit.)
- 인화점
- 175 °F
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 에 용해됨클로로포름, 메탄올 (약간 용해됨)
- 산도 계수 (pKa)
- 14.49±0.20(Predicted)
- 물리적 상태
- 액체
- 색상
- 무색~담황색 투명
- Specific Gravity
- 1.11
- optical activity
- [α]20/D +17.5°, c = 2.4 in methanol
- 수용성
- 녹는
- BRN
- 4652609
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- InChIKey
- XDPCNPCKDGQBAN-BYPYZUCNSA-N
- LogP
- -0.784 at 22℃ and pH6.8
- 표면장력
- 72mN/m at 1g/L and 25℃
- CAS 데이터베이스
- 86087-23-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
(S)-(+)-3-하이드록시 사하이드로 퓨란 C화학적 특성, 용도, 생산
개요
(S)-(+)-3-Hydroxytetrahydrofuran (3-OH THF) is a colorless liquid with a normal boiling point of 179 °C and boiling at 88-89 °C at 17 mmHg, with density (1.087 g/cm3 at 19 °C). 3-OH THF is a useful pharmaceutical intermediate. The chiral (absolute configuration S) version of this compound is an intermediate to launched retroviral drugs.화학적 성질
Colourless Liquid용도
(S)-(+)-3-Hydroxytetrahydrofuran is a useful reagent for the preparation of pyrazolo triazin ylamine derivatives as adenosine receptor antagonists.Synthesis
(S)-(+)-3-Hydroxytetrahydrofuran was prepared from the reaction of (S)-1,2,4-butanetriol under hydrochloric acid modified montmorillonite catalyst. The steps were as follows:To the heatable reactor (with stirring device), 100g (S)-1,2,4-butanetriol, 200mL toluene, 15g hydrochloric acid modified montmorillonite catalyst prepared in were added successively. The reaction was stopped after 4 h at 110°C. After the reaction is finished, it is naturally cooled to room temperature, and the obtained material is filtered to recover the catalyst. After collecting the filtrate, the remaining solvent and by-product water in the filtrate are distilled off to obtain (S)-3-hydroxytetrahydrofuran crude product. Quantitative analysis was carried out by gas chromatography, and the yield was 96.8%. Finally, the (S)-3-hydroxytetrahydrofuran was obtained by rectification and purification.![S)-(+)-3-Hydroxytetrahydrofuran synthesis S)-(+)-3-Hydroxytetrahydrofuran synthesis](/NewsImg/2023-11-09/6383512312542398087160792.png)
(S)-(+)-3-하이드록시 사하이드로 퓨란 준비 용품 및 원자재
원자재
준비 용품
(S)-(+)-3-하이드록시 사하이드로 퓨란 공급 업체
글로벌( 719)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Suzhou Ryan Pharmachem Technology Co.,Ltd. | +86-512-68780025 +8618962125825 |
sales@ryanchem.com | China | 137 | 58 |
Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 |
Ryan@jiutian-bio.com | China | 7431 | 58 |
Porton Pharma Solutions Ltd. | |
China | 56 | 58 | |
Lianhe Aigen Pharmatech Co.,Ltd. | +undefined+undefined18918657159 |
sales-Aigen@lianhetech.com | China | 309 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12449 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 |
peter@yan-xi.com | China | 5872 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5870 | 58 |
Shanghai Joiny Pharmaceutical Co.,LTD | +8613681955282 |
gyd@joiny-pharma.com | China | 249 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 |
sales06@hbduling.cn | China | 8078 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
(S)-(+)-3-하이드록시 사하이드로 퓨란 관련 검색:
테트라하이드로푸란 2-메틸테트라하이드로퓨란 디시클로펜타디에닐 철 (S)-(+)-3-하이드록시 사하이드로 퓨란
3-(S)-HYDROXY TETRAHYDROFURAN
POLY(TETRAHYDROFURAN) STANDARD 15000
3-HYDROXYTETRAHYDROFURAN 99%,3-HYDROXYTETRAHYDROFURAN
(R)-(+)-3-HYDROXYTETRAHYDROFURAN-2-ONE
α-D-erythro-Pentofuranose-2-deoxy-2,2-difluoro-3,5-dibenzoate
(S)-4-HYDROXYTETRAHYDROFURAN-2-ONE,4(S)-Hydroxytetrahydrofuran-2-ONE
3-HYDROXYTETRAHYDROFURAN-2-ONE,2-Hydroxytetrahydrofuran-2-one
(R)-(-)-3-HYDROXYTETRAHYDROFURAN,(R)-3-HYDROXYTETRAHYDROFURAN
((2R,3S,5R)-5-(5-(3-Aminopropyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
(2S, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL
(2R, 4R)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL
(2R, 4S)-4-HYDROXYTETRAHYDROFURAN-2-METHANOL
(3R)-3β,4α-Bis(3-methoxy-4-hydroxybenzyl)-3-hydroxytetrahydrofuran-2-one
(S)-(+)-3-HYDROXYTETRAHYDROFURAN-D4